Manager, Accounting

Spyglass Pharma•Irvine, CA

About The Position

SpyGlass Pharma is seeking an Accounting Manager to join their growing Finance & Accounting team. This role will be responsible for managing core accounting functions, including payroll, general ledger maintenance, accounts payable/receivable, month-end close, and budget oversight. As SpyGlass scales, this position will play a key role in refining financial processes to support growth. This is a high-impact, hands-on role in a pre-revenue, R&D-focused environment, ideal for someone who thrives in fast-paced startups and is excited about working in a dynamic, evolving finance function.

Requirements

  • Bachelor’s degree in Accounting, Finance, or a related field; CPA preferred.
  • 5-8+ years of accounting experience, ideally in startups, biotech, or life sciences.
  • Strong understanding of GAAP, payroll processing, and pre-revenue financial reporting.
  • Hands-on experience with AP, AR, payroll, tax compliance, and financial statement preparation.
  • Familiarity with stock-based compensation and equity accounting.
  • Proficiency with NetSuite, QuickBooks, or other accounting software.
  • Advanced Microsoft Excel skills
  • Strong analytical and problem-solving skills, with the ability to work independently in a fast-moving environment.
  • Excellent communication and collaboration skills, with a proactive and adaptable mindset.

Nice To Haves

  • Experience with venture-backed startups, investor reporting, and fund tracking is a plus.
  • Public company experience related to supporting audits, SOX compliance and internal controls preferred.

Responsibilities

  • Oversee payroll administration, ensuring accurate and timely payroll processing, compliance with tax regulations, and benefits accounting.
  • Oversee and manage travel & entertainment program administration including employee expense reporting, approval, and reimbursement.
  • Manage day-to-day accounting operations, including general ledger maintenance, reconciliations, and financial statement preparation.
  • Lead the month-end and year-end close processes, including journal entries, accruals, and financial reporting.
  • Oversee accounts payable, accounts receivable, and cash management, ensuring efficient processes for vendor payments and expense tracking.
  • Maintain and refine internal controls, accounting policies, and procedures to ensure compliance and scalability.
  • Assist with budgeting, forecasting, and financial modeling, partnering closely with the VP of Finance.
  • Prepare financial reports and investor updates, supporting fundraising and equity-related accounting.
  • Support audit and tax compliance, including coordination with external auditors and tax advisors.
  • Implement and optimize financial systems and automation tools to improve efficiency.

Benefits

  • Annual Bonus opportunity
  • Stock options
  • Comprehensive health, dental, and vision insurance plans
  • Generous paid time off, including holidays, vacation days, and personal leave.
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