LEUKINE® Melanoma Program Team Leader (Executive Director)

Partner Therapeutics•Lexington, MA

6d•$200,000 - $280,000•Hybrid

About The Position

The LEUKINE® Melanoma Program Team Leader (PTL) is the end-to-end business owner responsible for launch readiness of LEUKINE® in metastatic melanoma, starting with a focus on supply chain and regulatory readiness. The PTL will be accountable for the product’s performance across the full lifecycle, from late-stage development and registration through launch and commercialization to lifecycle expansion and supply continuity. A matrixed leader, the PTL is responsible for closely aligning with functional leaders to ensure program objectives are met. This role carries full P&L responsibility and operates as the program’s general manager, integrating strategy and execution across CMC/Supply Chain, Clinical Development, Regulatory, Market Access, Medical Affairs, and Commercial functions.

Requirements

Business & Financial Acumen - Strong analytical and financial instincts, with the ability to translate market insights into actionable business strategies. Highly organized, with a proven ability to prioritize effectively, manage budgets, and deliver results on time; grounded in the principles of operational excellence.
Strategic & Critical Thinking - A results-oriented, innovative thinker who brings strong problem-solving skills and sound judgment to complex challenges. Thrives in fast-paced environments and consistently moves teams forward with purpose and clarity.
Communication & Influence - Exceptional communicator including written, verbal, and in presentation with the ability to engage, persuade, and align audiences at all levels of the organization. Runs effective meetings and fosters open, productive dialogue.
Interpersonal Effectiveness - Brings a bias toward action, a consistently constructive outlook, and genuine comfort working across diverse teams and functions. Gives and receives feedback openly, adapts readily to change, and approaches unexpected challenges with composure.
Regulatory Navigation - Adept at operating within complex regulatory environments, ensuring adherence to applicable laws and regulations while managing multiple priorities and projects simultaneously.
Technical Proficiency - Strong Microsoft Office skills (Word, Excel, PowerPoint, Outlook) and quick to adopt new tools and applications as business needs evolve.
Bachelor’s Degree
15+ years of progressively responsible experience in leadership or management consulting roles within biopharma industry primarily in team leadership, portfolio or program management (Master’s degree or equivalent in related field may substitute for 3 years of professional experience; terminal degree may substitute for 5 years of professional experience.)

Nice To Haves

Advanced professional degree in life sciences (Ph.D., M.D., Pharm.D., MBA)

Responsibilities

Owns full P&L including revenue, gross-to-net, operating expenses, and profitability with an initial focus on launch investment prioritization and management
Leads integrated launch planning across all elements of the supply chain, regulatory, development, medical affairs and commercial defining clear deliverables and accountability
Plans and executes on the most optimal launch that maximizes market uptake, patient adoption/convenience, guideline adoption as well as generation of value for PTx
Drives forecasting, scenario planning, and risk management
Authors key product development plans with clear goals, timelines, go/no-go decision points and target product profiles for clarity across the organization
Oversees execution of plan deliverables and implements subteams as needed
Chairs cross-functional melanoma program team and ensures alignment across functions and key interdependencies
Presents regular updates to Executive Leadership Team
Develops and executes communication plan (including publications, presentations, and press relations).
Ensures supply readiness and lifecycle supply reliability for melanoma launch
Ensures clear regulatory strategies to support new manufacturing process and new presentation at launch in US, EU, Australia and other target markets
Evaluates path to create a new sargramostim brand for melanoma (e.g. formulation, flat dosing, presentation) and relevant regulatory strategy
Ensures clear presentation lifecycle strategy, including DoW funded autoinjector. Garners customer insight to guide presentation decisions.
Manages capacity, inventory, and manufacturing risks
Defines approval strategy and labeling approach in US and ex-US as well as optimal launch sequence
Aligns regulatory strategy with access and commercial needs and articulates plans to fill gaps
Ensures on time submission of key regulatory filings per plan
Defines labeling strategy
Identifies and articulates plan to fill registration gaps in key markets
Prepares development plan to expand indications
Shapes integrated pre-launch strategy and launch strategy as well as tactics in partnership with all key stakeholders; ensures aligned prioritization of cross-functional tactics to realize plan, including launch sequence
Sets revenue targets and aligns incentives
Defines global pricing strategy with Market Access team
Ensures that all launch activities are designed and executed in full alignment with applicable US and international regulatory requirements
Leads and develops PTx Partners - Builds and inspires a high-performing, inclusive team where people feel empowered to do their best work and grow continuously. Provides timely, honest performance feedback; recognizes and rewards high achievement; and addresses underperformance with clarity and care
Sets clear direction - Establishes cross-functional program goals, performance targets, and metrics that align with organizational priorities and ensures the team has the capabilities and capacity to deliver on them.
Plans resources strategically - Identifies and recommends the human, financial, and technical resources needed to meet near- and long-term commitments while building toward lasting excellence.
Communicates consistently - Maintains regular, two-way dialogue with program team members to keep goals, priorities, and expectations clear and mutually understood.
Models the PTx culture - Leads by example, embodying PTx's core values - a passion for patient care, a commitment to excellence, relentless curiosity, and deep respect for all people - and brings those values to life through a strong culture of quality, accountability, and continuous improvement.
Upholds compliance - Coaches and holds the team accountable for meeting all regulatory, quality, safety, and cGMP requirements, ensuring every team member has the training, knowledge, and skills to perform their role with confidence and integrity.