Lead Bioinformatics Engineer

Quest DiagnosticsBaltimore, MD
$130,000 - $160,000Hybrid

About The Position

We are a leading oncology diagnostics company dedicated to advancing precision medicine through cutting edge ultra-sensitive genomic technologies. As we expand our portfolio of minimal residual disease (MRD) testing solutions, we are seeking a highly skilled and motivated Senior Bioinformatics Engineer to join our team. This role offers the opportunity to contribute to the development and implementation of bioinformatics methods that directly impact cancer patient care, enabling improved monitoring, and more informed treatment decisions. The Senior Bioinformatics Pipeline Engineer will design, architect, optimize, and scale our clinical-grade Next-Generation Sequencing Bioinformatics workflows. As a senior technical contributor, you will bridge the gap between assay development, assay validation, and clinical informatics systems. You will lead the implementation of automated computational workflows that process massive genomic datasets, ensuring the rapid, accurate, and secure delivery of diagnostic insights. Operating within a regulated clinical laboratory environment, you will champion modern software engineering practices, Infrastructure as Code (IaC), containerization, and advanced cloud orchestration to ensure high reproducibility, robust security, and absolute compliance with CAP, CLIA, NYSDOH, and FDA regulations.

Requirements

  • Highly skilled and motivated Senior Bioinformatics Engineer
  • Experience in designing, architecting, optimizing, and scaling bioinformatics workflows.
  • Ability to bridge the gap between assay development, assay validation, and clinical informatics systems.
  • Experience leading the implementation of automated computational workflows for processing large genomic datasets.
  • Familiarity with modern software engineering practices.
  • Experience with Infrastructure as Code (IaC).
  • Experience with containerization.
  • Experience with advanced cloud orchestration.
  • Understanding of CAP, CLIA, NYSDOH, and FDA regulations.

Responsibilities

  • Design, architect, optimize, and scale clinical-grade Next-Generation Sequencing Bioinformatics workflows.
  • Bridge the gap between assay development, assay validation, and clinical informatics systems.
  • Lead the implementation of automated computational workflows that process massive genomic datasets.
  • Ensure the rapid, accurate, and secure delivery of diagnostic insights.
  • Champion modern software engineering practices, Infrastructure as Code (IaC), containerization, and advanced cloud orchestration within a regulated clinical laboratory environment.
  • Ensure high reproducibility, robust security, and absolute compliance with CAP, CLIA, NYSDOH, and FDA regulations.

Benefits

  • Day 1 Medical, supplemental health, dental & vision for FT employees who work 30+ hours
  • Best-in-class well-being programs
  • Annual, no-cost health assessment program Blueprint for Wellness®
  • healthyMINDS mental health program
  • Vacation and Health/Flex Time
  • 6 Holidays plus 1 "MyDay" off
  • FinFit financial coaching and services
  • 401(k) pre-tax and/or Roth IRA with company match up to 5% after 12 months of service
  • Employee stock purchase plan
  • Life and disability insurance, plus buy-up option
  • Flexible Spending Accounts
  • Annual incentive plans
  • Matching gifts program
  • Education assistance through MyQuest for Education
  • Career advancement opportunities
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