This position has a term length of 1 year plus 1 day. The Laboratory Technician will use 3D-suspension culture methods to optimize beta-cell differentiation protocols and deliver scale-up of these endocrine cells. Diabetes is a global health problem worldwide with a huge economic burden. Cell therapies, such as induced pluripotent stem cells could provide a replenishable source of beta cells. Optimized methods and scale-up strategies for human stem cell-derived beta cells could potentially translate this into clinical therapy. Progressive deterioration of pancreatic beta cells is a hallmark of both type -1 and -2 diabetes. Stem cell therapy shows great promise and has a clear proof of concept to reverse diabetes, but with a limitation of production of sufficient tissue mass for transplant. More advanced methods could lead to scale-up and mass production of reliable stem cell-derived beta cells without off-target cells.
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Job Type
Full-time
Career Level
Mid Level
Education Level
No Education Listed
Number of Employees
1-10 employees