Laboratory Manager | Laboratory of Host-Pathogen Biology

Rockefeller University•New York, NY

1d•Onsite

About The Position

Under direction from the Laboratory Head, the Laboratory Manager will perform research and lab administration in the Laboratory of Host-Pathogen Biology at Rockefeller University. Our lab has developed novel CRISPR-based tools for functional genomics in the globally important pathogen, Mycobacterium tuberculosis. At Rockefeller, you will join a dynamic research team to investigate the mechanisms that enable this bacterium to cause disease and evade current antibiotics, with the long-term goal of developing new strategies to improve control of this pandemic.

Requirements

Master’s in Microbiology or a closely related field (or a foreign degree equivalent)
2 years of experience with management and coordination of multi-institutional, internationally funded tuberculosis research projects (grant compliance, progress reporting, and laboratory team coordination).
Proficiency in tuberculosis molecular microbiology and genetic analysis.
Ability to conduct research in high-containment biosafety level-3 (BSL-3) laboratory.
Skills with molecular assay development for antibiotic-resistance studies, and microbiological and analytical techniques (DNA and RNA extraction, quantitative PCR, electrophoresis, protein analysis, and flow cytometry).
Ability to develop and optimize laboratory-based diagnostic and experimental assays for tuberculosis research.

Responsibilities

Oversee and advance research on the biology of Mycobacteria, focusing on functional genomics, antibiotic resistance, and host–pathogen interactions.
Integrate experimental design, laboratory compliance, and grant administration.
Conduct CRISPRi-based genetic perturbation experiments and functional genomics studies to investigate mycobacterial biology.
Perform molecular cloning, PCR, gene expression analysis, DNA/RNA isolation, deep sequencing, and metabolomics.
Develop and optimize new experimental protocols and standard operating procedures (SOPs).
Analyze and interpret data, contributing to publications in peer-reviewed scientific journals.
Handle daily operations of a research laboratory.
Handle project management, including managing expenditures and ensuring compliance with funding agencies.
Prepare financial justifications and grant compliance documentation for institutional and sponsor requirements.
Coordinate multi-disciplinary teams in preparing and submitting research grant proposals.