Lab Technician or Specialist, Lu Lab - Cell Biology

UVA Health•Charlottesville, VA

48d•$19 - $22•Onsite

About The Position

The Lu lab in the Department of Cell Biology at the University of Virginia seeks a Lab Technician or Specialist (level depending on experience) to investigate molecular and cellular mechanisms underlying the development of inner ear sensory hair cells and congenital deafness. The lab has a long-standing interest in how Wnt / Planar Cell Polarity (PCP) signaling pathways and cell polarity proteins regulate hair cell cytoskeletal organization. We have developed a multidisciplinary approach using biochemistry in vitro, ex vivo organ culture, fluorescence live imaging, and mouse genetics for mechanistic investigation of deafness and other common congenital birth defects such as neural tube defects (NTD). The Lu lab has multiple NIH-funded projects and fosters a respectful and supportive environment dedicated to research and education. The new team member will work closely with Dr. Lu and other lab members. They will attend lab and project meetings weekly or more often as necessary. They will be trained and receive guidance and will be expected to interact professionally and collegially with all lab members including graduate and undergraduate students, treating all lab members with respect and consideration.

Requirements

Associate's degree required plus 2 years of experience
Bachelor’s degree and 2+ years of experience preferred.

Nice To Haves

Possess excellent attention to detail and strong problem solving and record-keeping skills.
Be a clear and honest communicator and be motivated to learn new laboratory skills and contribute to lab projects.
Have knowledge of basic cell biology and biochemistry.
Demonstrated experience working with mice and maintaining a mouse colonies.
Some experience with biochemical or cell-based assays and molecular biology techniques such as PCR and in situ hybridization would be highly preferred.

Responsibilities

Facilitate research of mouse models for hearing loss.
Perform immunohistochemistry and cochlear explant assays, abr (auditory brainstem response) testing and maintenance of the mouse colony.
Assist in molecular and cell biology experiments, including recombinant dna construction, in situ hybridization, cell culture, transfection, and viral-mediated transduction.
Work with other team members to maintain mice/cells, carry out experiments, analyze data, as well as documenting and reporting on results to the group.
Routine lab maintenance and administration tasks.