Instructor – Post-Doctoral Fellow (One Year Pre-Residency)

University of Colorado•Aurora, CO

8d•Hybrid

About The Position

This is a one-year postdoctoral position situated in the new Pre-Resident Postdoctoral Research Fellowship Program in the Department of Orthopedics. Responsibilities will primarily involve management of projects aimed at understanding the influence of obesity on the molecular and cellular behavior of the synovium in various synovial joints. Work will encompass management of human tissue collection protocols, nucleic acid extraction from this tissue for RNA sequencing and epigenetic study, and contribution, with mentoring, to data analysis. There will also be involvement in other projects in the Foot and Ankle Division and the Orthopedic Research Center, which may include patient-reported outcomes analyses, biomechanical studies and studies of osteoarthritis.

Requirements

An MD or DO degree
Experience in research

Nice To Haves

Research experience in translational or clinical orthopedics
Experience collecting and processing human tissue samples
Experience performing tissue, protein and nucleic acid isolation and analyses
Bioinformatics experience
Interest in inclusion of research and discovery as part of career plan
Interest in pursuing a Residency in Orthopedic Surgery
Basic knowledge of statistics
Understanding of skeletal system biology
Ability to work both in a team environment and independently
Strong organizational and record-keeping skills
Strong communication skills, both verbal and written
Basic computer skills in both Mac and PC environments

Responsibilities

Work with human protocols, including initial submission, presentations to the Scientific Advisory Research Committee, modifications, and regulatory oversight
Collecting surgical discarded synovial tissue
Performing nucleic acid extraction procedures, integrity testing, and quantification for both RNA and DNA
Tissue preparation and processing for paraffin-based histology
Molecular analyses of human tissues, including immunohistochemistry and immunofluorescence
Preparation of abstracts and manuscripts
Participation in preparation of research grants
Participation in research related coursework and resident labs and didactic series