Imaging Data Scientist III

Children's Hospital of PhiladelphiaPhiladelphia, PA
$126,560 - $167,690Onsite

About The Position

Seeking Breakthrough Makers Children’s Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation. At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care—and your career. CHOP does not discriminate on the basis of race, color, sex, national origin, religion, or any other legally protected categories in any employment, training, or vendor decisions or programs. CHOP recognizes the critical importance of a workforce rich in varied backgrounds and experiences and engages in ongoing efforts to achieve that through equally varied and non-discriminatory means. A Brief Overview We are seeking an Imaging Data Scientist III to lead development of scalable imaging pipelines, infrastructure, and computational workflows for large-scale multi-institutional pediatric neuro-oncology and translational imaging studies. This position will support cutting-edge artificial intelligence (AI), machine learning (ML), and multimodal imaging research focused on improving diagnosis, risk stratification, treatment response assessment, and clinical decision support for pediatric brain tumors. The successful candidate will work closely with multidisciplinary teams of clinicians, imaging scientists, data scientists, software engineers, and computational biologists to design and implement robust imaging analytics infrastructure capable of supporting large-scale collaborative research initiatives and clinical translation.

Requirements

  • Master’s degree or PhD in Biomedical Engineering, Computer Science, Data Science, Medical Imaging, Bioinformatics, or a related quantitative field.
  • At least five (5) years of of applied algorithm development, data science, applied statistics, machine learning, or mathematical modeling projects experience
  • Significant experience developing computational pipelines and infrastructure for medical imaging analysis.
  • Strong programming skills in Python and/or related scientific computing languages.
  • Experience working with medical imaging formats and frameworks (e.g., DICOM, NIfTI, MONAI, ITK, SimpleITK, NiBabel).
  • Experience with cloud computing platforms, containerization, and workflow orchestration technologies (e.g., Docker, AWS, Airflow, or similar).
  • Familiarity with machine learning and deep learning methods for imaging analysis.
  • Experience working with large-scale, multi-institutional biomedical datasets.
  • Expert proficiency with formulating analysis plans and selecting appropriate methods
  • Expert proficiency with machine learning and analytic tools (e.g., ScikitLearn, PyTorch, …)
  • Expert proficiency with programing languages (Python)
  • Expert proficiency with writing code in applied academic or professional projects
  • Expert proficiency with creating informative visualizations for complex, high dimensional data
  • Substantial knowledge of biological and medical domains
  • Excellent verbal and written communications skills
  • Ability to maintain confidentiality and professionalism
  • Ability to work independently with minimal supervision
  • Ability to gather, analyze and make recommendations/decisions based on data / best practices
  • Ability to convey complex or technical information in an easy-to-understand manner
  • Ability to collaborate with stakeholders at all levels

Nice To Haves

  • PhD in Biomedical Engineering, Computer Science, Data Science, Medical Imaging, Bioinformatics, or a related quantitative field
  • Experience in pediatric neuro-oncology or neuroimaging research.
  • Experience with imaging harmonization, federated learning, or distributed data infrastructures.
  • Familiarity with multimodal AI frameworks integrating imaging, clinical, and molecular data.
  • Experience with MLOps, software engineering best practices, and deployment of research tools into production environments.
  • Prior leadership or team management experience.
  • Track record of peer-reviewed publications and collaborative research contributions.
  • Intermediate proficiency with distributed computing technologies (Akka, MapReduce, Cuda)
  • Intermediate proficiency with probabilistic graphical, time series predictive, statistical/mathematical and Markov models
  • Substantial knowledge of relational databases
  • Substantial knowledge of web services application programming interfaces
  • Substantial knowledge of graph, key value, and document data stores

Responsibilities

  • Lead development and maintenance of scalable, cloud-enabled imaging pipelines and computational infrastructure for multi-institutional imaging studies.
  • Design and implement automated workflows for medical imaging data ingestion, harmonization, preprocessing, quality control, storage, and analytics.
  • Develop infrastructure for management and analysis of large-scale multimodal datasets, including MRI, digital pathology, clinical, and molecular data.
  • Collaborate with investigators and consortium partners to support standardized imaging analysis across diverse institutions and datasets.
  • Build reproducible and containerized workflows using modern software engineering and MLOps practices.
  • Support development, deployment, and optimization of AI and machine learning models for medical imaging applications.
  • Contribute to technical platform development for cloud-based and high-performance computing environments.
  • Assist with integration of imaging-derived biomarkers with clinical, genomic, and other multimodal data for predictive modeling.
  • Mentor junior analysts, trainees, and research staff in imaging analytics and computational workflow development.
  • Contribute to grant applications, manuscripts, technical documentation, and collaborative scientific initiatives.

Benefits

  • As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must receive an annual influenza vaccine.
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