Head of Oncology Medical Affairs Business Operations

Pfizer • San Diego, CA

6d • $214,900 - $358,100

About The Position

Reporting to the Chief Oncology Medical Officer, the Head of Oncology Medical Affairs Business Operations leads the day-to-day business operations, planning, governance, resource management, communications, and organizational enablement needed to advance Oncology Medical Affairs priorities. As a member of the Oncology Medical Affairs Leadership Team (OMALT), the role acts as an operational partner to the Chief Oncology Medical Officer and works across Medical Affairs, Oncology, Research, Development, Commercial, People Experience, Finance, Communications, and other enabling functions to translate priorities into coordinated execution.

The role combines business acumen, operational leadership, and understanding of the scientific and healthcare environment to strengthen leadership effectiveness, remove barriers, manage dependencies, and enable measurable impact for patients and the oncology community. Responsibilities span business planning and execution, leadership team governance, cross-functional initiatives, resource and FTE planning, organizational effectiveness and talent, stakeholder communications, and responsible use of AI and digital tools to improve operational efficiency.

The position is eligible for Pfizer’s Global Performance Plan with a 22.5% bonus target and participation in its share-based long-term incentive program. Pfizer offers comprehensive benefits, including retirement savings contributions, paid time off, caregiver/parental and medical leave, and health coverage. Relocation assistance may be available based on business needs and eligibility. Candidates must have permanent U.S. work authorization; U.S. work visa sponsorship is not available.

Requirements

• Bachelor’s degree and 12 or more years of relevant experience; or a master’s degree, MBA, MPH, PharmD, or equivalent and 10 or more years of relevant experience; or a PhD and 7 or more years of relevant experience.
• Relevant experience in the biopharmaceutical industry, healthcare, Medical Affairs, R&D operations, business operations, strategy, or a related field.
• Demonstrated experience leading complex cross-functional initiatives and delivering results in a global, highly matrixed organization.
• Strong business planning, operational leadership, project and portfolio management, organizational effectiveness, and stakeholder management capabilities.
• Exceptional written, verbal, presentation, and executive communication skills, with judgment and discretion when working with senior leaders and sensitive information.
• Ability to influence without direct authority, manage competing priorities, and turn ambiguous or complex objectives into clear plans, decisions, and measurable outcomes.
• Demonstrated proficiency in regularly and responsibly using AI and digital productivity tools to improve work quality, speed, and effectiveness.
• Permanent work authorization in the United States; U.S. work visa sponsorship is not available.

Nice To Haves

• Oncology or Medical Affairs experience and understanding of evidence generation, scientific communications, patient-centered medical strategy, and the healthcare ecosystem.
• Experience in Business Operations, Development Business Operations (DBO), strategy, program leadership, or organizational effectiveness supporting a senior executive or leadership team.
• Experience with FTE planning, workforce capacity management, resource allocation, and organizational prioritization.
• Experience leading organizational change, business transformation, capability building, or leadership team effectiveness initiatives.
• Demonstrated ability to apply AI, advanced analytics, and digital tools to business operations, decision support, communications, or process improvement.
• Experience leading and developing colleagues or teams, including resources operating through matrix relationships.
• Strong business acumen, executive presence, sound judgment, organizational maturity, and ability to build trusted relationships with internal and external stakeholders.

Responsibilities

• Lead day-to-day business operations for the Chief Oncology Medical Officer, including prioritizing and coordinating interactions, meetings, presentations, deliverables, and organizational commitments.
• Anticipate operational needs, surface risks and dependencies, and ensure timely follow-through on decisions and actions.
• Lead annual, semester, and longer-range Oncology Medical Affairs business planning, including development, alignment, implementation, and tracking of goals, success measures, and execution plans.
• Provide visibility into progress, risks, interdependencies, and required decisions.
• Lead OMALT’s operating rhythm, including agendas, strategic reviews, offsites, decision governance, action tracking, and accountability mechanisms.
• Continuously improve leadership team processes to focus on high-value priorities and strengthen collaboration and execution.
• Lead or coordinate high-priority business and organizational initiatives on behalf of the Chief Oncology Medical Officer.
• Build partnerships across global, regional, and country Medical Affairs and with Oncology, Research, Development, Commercial, People Experience, Finance, Communications, and other enabling functions to align stakeholders and deliver outcomes.
• Coordinate resource and FTE planning across Oncology Medical Affairs, helping leaders assess capacity, capabilities, trade-offs, and deployment against strategic priorities.
• Maintain visibility into resource needs and support disciplined prioritization and organizational decision-making.
• Partner with People Experience and leaders on workforce and talent planning, succession, leadership development, colleague engagement, onboarding, leadership transitions, and organizational effectiveness.
• Help foster a culture of inclusion, accountability, collaboration, innovation, and continuous improvement.
• Partner with Communications to develop executive presentations, briefing materials, talking points, town halls, organizational updates, site visits, and other internal and external engagements.
• Develop a strong understanding of Pfizer Oncology strategy, Medical Affairs priorities, evidence-generation activities, and organizational capabilities.
• Regularly use AI, digital tools, and advanced analytics to improve planning, insight generation, communications, decision support, and operational efficiency.
• Promote responsible adoption of AI-enabled ways of working in accordance with Pfizer policies and applicable requirements, and identify opportunities to simplify processes and improve organizational impact.

Benefits

• 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
• Paid vacation, holidays, and personal days
• Paid caregiver/parental and medical leave
• Medical, prescription drug, dental, and vision coverage
• Participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of base salary
• Eligibility to participate in Pfizer’s share-based long-term incentive program
• Relocation assistance may be available based on business needs and/or eligibility

What This Job Offers

• Job Type: Full-time
• Career Level: Senior