Head of Integrated Safety Analysis (ISA)

General Matter•Los Angeles, CA

5d•Onsite

About The Position

General Matter is enriching uranium in America. Our goal is to design, build, and operate the world’s lowest-cost enrichment services in the United States. Our mission is to restore America’s ability to produce nuclear fuel—fuel that will power AI, advanced manufacturing, critical industries, and the next generation of nuclear reactors. Ultimately, our work will help power national ambitions and enable a high-energy society. We were incubated by Founders Fund, like Anduril and Palantir before us, and are backed by top-tier investors. Our lean, world-class team of engineers and operators is applying a first-principles approach to solving the problem of nuclear fuel production. We are a mission-driven company with a culture of urgency, accountability, and transparency. Help us build a high-energy society by making the cleanest, safest form of baseload energy the most affordable. We are seeking an experienced Integrated Safety Analysis (ISA) Leader to shape the safety foundation for a new NRC-licensed uranium enrichment facility regulated under 10 CFR Part 70. This is a rare opportunity to expand our ISA program, influence facility design from early engineering through operations, serve as a key technical partner to the NRC, and develop a high-performing safety analysis team supporting a critical domestic nuclear fuel capability.

Requirements

Bachelor's degree in chemical, mechanical, nuclear, or related engineering field; advanced degree preferred
8+ years in nuclear safety analysis, process safety, or a comparable high-hazard environment, including 3+ years in a leadership or lead technical role
Experience developing or materially contributing to an ISA, SAR, or equivalent safety basis
Expertise in ISA and PHA methods such as HAZOP, What-If, and FMEA; familiarity with criticality, fire, and external hazard analyses
Experience working with regulators and translating complex requirements into executable program
Excellent communication skills, both written and verbal, for conveying technical safety data to diverse audiences.
Ability to work collaboratively across engineering, operations, and licensing teams.

Nice To Haves

Direct experience with NRC 10 CFR Part 70 licensing and guidance, including NUREG-1513 and NUREG-1520
Experience with fuel-cycle facilities, enrichment operations, or nuclear chemical processes
Prior ISA, safety analysis, or licensing leadership at an NRC-licensed facility
Experience building safety programs in startup, greenfield, or rapid-growth environments
Knowledge of uranium enrichment technologies, vacuum systems, cryogenics, or compressible flow
PE, CSP, NRC criticality safety qualification, or other relevant credential

Responsibilities

Build, own, and continuously improve the ISA program in accordance with 10 CFR Part 70 Subpart H
Develop program procedures, standards, tools, training, and risk-informed decision-making practices
Set the technical direction for ISA, IROFS, Management Measures, and the facility safety basis
Build, mentor, and manage a team of ISA engineers and safety analysts
Lead the ISA Summary, Safety Analysis Report, license application materials, and responses to NRC requests
Serve as the primary technical contact for NRC audits, inspections, and review meetings
Lead hazard identification, accident sequence modeling, consequence analysis, likelihood determination, and PHAs using HAZOP, What-If, FMEA, and related methods
Oversee risk assessments for nuclear criticality, chemical and fire hazards, natural phenomena, and external events
Review and maintain IROFS and Management Measures, ensuring design and operational changes receive appropriate safety evaluation
Partner with engineering, operations, licensing, quality, and criticality safety teams to shape facility decisions from design through commissioning, startup, and operations
Advise company leadership on safety risk, regulatory strategy, and high-impact design decisions