Head of Health, Economics & Outcomes Research (HEOR)

argenx

1d•$328,000 - $451,000•Remote

About The Position

Join argenx as we transform immunology and deliver medicines that help autoimmune patients get their lives back. argenx is preparing for multi-dimensional expansion to reach more patients through a rich pipeline of differentiated assets, led by VYVGART, our first-in-class neonatal Fc receptor blocker approved for the treatment of gMG, and with the potential to treat patients across dozens of severe autoimmune diseases. We are building a new kind of biotech company, one that maintains its roots as a science-based start-up and pushes our commitment to innovate across all corners of our business. We strive to inspire and grow our company, our partnerships, our science, and our people, because when we do, we deliver more for patients. argenx is focused on developing and commercializing product candidates with the potential to be either first-in-class against novel targets or best-in-class against known, but complex targets to treat immunologic diseases with significant unmet medical need. Changes in healthcare systems with advances in medicine and health technologies have increased the need for value-evidence to support decision making regarding the adoption of innovative therapies by various stakeholders. argenx is committed to elucidating the burden of illness faced by patients and caregivers for conditions we seek to address and providing evidence of the value of our treatments for these diseases. This will enable us to prepare for successful product launches and sustained market access to our medicines and includes generating and communicating evidence to answer questions from healthcare decision makers such as regulators, payors, Health Technology Assessment (HTA) authorities, HCPs, patient advocacy organizations, and other stakeholders in alignment with the broader strategies for our therapies. The Head, Health Economics & Outcomes Research (HEOR) leads and organizes a team of scientists and specialists to develop value-evidence supporting a large and growing portfolio. This person will collaborate with internal and external stakeholders and decision makers to lead and support the planning, design, and execution of HEOR deliverables across all phases of drug development for more than 20 pipeline and marketed indications, working with Development and Commercialization teams globally. This individual will lead the HEOR capability and collaborate cross-functionally with the other capabilities including Real World Evidence (RWE), Clinical Development, Medical Affairs & Evidence Generation (MA&EG), Market Access, Commercial, Patient Advocacy, Business Development, and Regulatory to align evidence generation efforts with identified evidence gaps. The Head, HEOR will have broad responsibility to support scientifically credible HEOR work and deliverables. This includes partnering with external clinical and research experts and patient advocates. The individual will be expected to understand and engage with colleagues across the organization to provide the necessary insights to guide value-evidence needs for molecules in development and value-evidence possibilities for commercialized products aligned with defined strategy. Importantly, the Head of HEOR is responsible for developing the strategy for capability excellence at argenx, not only in the short-term but also for the long-term considering the evolving technology environment, expanding portfolio, and access landscape globally. This includes cross-functional collaboration to effectively define capability scope, budget and timelines to support a team that produces and disseminates relevant, targeted, and timely value evidence across argenx markets and for given conditions of interest. Additionally, this individual is a member of the MA&EG Leadership Team and co-owns achievement of the MA&EG vision at argenx and excellence of the MA&EG Community in achieving our goals.

Requirements

Advanced degree in Health Economics, Epidemiology, Health Services Research or a related discipline is required (e.g., PhD, MS, MPH).
Minimum 12 years consulting and/or working in pharmaceutical/biotech industry: knowledge of pharmaceutical development, scientific project management, HEOR methodology and required deliverables, evidence generation, and compliance and regulatory requirements.
Minimum 7 years HEOR experience: In depth understanding of project set up and execution from feasibility analysis, need determination, to full prospective study development, set up, governance, HCP/KOL/external stakeholder management, and execution.
Cross-functional team management and broad understanding of the use of evidence for maximum impact.
Experience working with markets worldwide, including US, Europe and Asia preferred.
Experience developing and leading a growing team of HEOR Scientists and supporting roles with a proven track record of capability leadership.
A history of leadership that empowers team members to manage their book of work and develop professionally for continued professional growth and development.
Ability to travel up to 30% of time as needed and spend some time each month in at least one argenx office

Nice To Haves

Technical Mastery: Has a thorough understanding and expertise across HEOR areas and experience supporting markets worldwide. Knowledge of and experienced in different types of HEOR studies, e.g. cost effectiveness, cost-utility, cost-benefit, and budget impact modeling, literature reviews and syntheses, comparative effectiveness research, observational noninterventional studies, prospective cohort studies, etc.
Leadership: Experience building and developing teams and individuals. Can develop others who are in different stages of their careers to produce successful outcomes and grow skills. Able to reflect on one’s own strengths and development areas. Pursues training and opportunities for growth to continuously build knowledge and skills. Shares expertise with and values empowerment of others. Able to navigate matrixed environments successfully.
Communication: Strong active listening skills and able to seek clarification when needed. Speaks clearly and persuasively in positive or negative situations. Writes clearly and informatively. Able to read and interpret written information and communicate HEOR data to a wide range of stakeholders.
Teamwork: Understand the value of co-creation and ability to seek input from and synthesize the needs of multiple stakeholders and across multiple markets. Balances team and individual responsibilities. Gives and welcomes feedback. Contributes to building a positive team spirit. Supports everyone's efforts to succeed. Contributes to building a positive team spirit. Shares expertise with others.
Innovation: Thinks about the evolving treatment landscape, rapidly changing technology environment, and multiple market needs to anticipate trends and adapt so that we can maximize the value story for our products. Knowledge of recent changes in payer and health technology assessment landscape and how we can meet requirements in a rapidly changing environment.
Adaptability: Manages competing demand. Changes approach or method to best fit the situation. Able to deal with change, delays, or unexpected events in a growing organization and an increasingly competitive environment.
Priority setting: Effectively sets clear priorities among competing opportunities. Leverages experience and know-how to focus on priority objectives. Able to balance short-term and long-term goals.
Thinking / Problem solving: Adopts an open approach and sense of curiosity to understand opportunities. Creates solutions by developing options that address stakeholder requirements or constraints in a constructive manner.

Responsibilities

Lead, align, and maintain HEOR evidence generation plans with RWE, Clinical Development, Regulatory, MA&EG, Market Access, and Commercialization demonstrating unmet patient need and the value of argenx treatments in multiple markets. These plans should be aligned with indication/molecule strategies and incorporated into the integrated evidence generation plans for the given indication/molecule in collaboration with MA&EG and data communication plans in collaboration with Scientific Communications.
Lead and mentor a team of HEOR scientists who develop strategic value evidence generation plans and execute them including the conduct and timing of analyses, timelines, and budget management. Working with internal stakeholders and external experts, develop impactful value-evidence generation plans and on time deliverables.
Lead HEOR organizational evolution to meet the needs of a growing commercialization organization with the anticipation of several new indication/molecule launches in multiple markets over the next few years, requiring close partnership with Market Access and Commercial to meet their needs. This will also require ongoing reduction of administrative burden and prioritization.
Partner closely with Market Access to align on local market evidence generation needs and key priorities for execution including their timely and coordinated delivery.
Support the team of HEOR Scientists to collaborate with argenx stakeholders broadly to identify, select, and execute value-evidence projects with consideration for Health Care Practitioner (HCP) and patient advocacy integration, regulatory concerns, legal, and compliance.
Lead HEOR connecting with the internal and external community to keep abreast of developments in the environment impacting stakeholder needs to direct value-evidence planning.
Lead broad evidence dissemination through high-quality publications in collaboration with investigators, HCPs/KOLs, and patient advocates as appropriate that will contribute to company discussions with and submissions to payers/HTAs.
Partner closely with argenx MA&EG, RWE, and Patient Advocacy to identify, enlist, and maintain the interest of HCPs/KOLs and Patient Advocacy Groups relevant to the disease states being studied to inform our work and/or partner on its execution.
Contribute as a member of the MA&EG Leadership Team to drive the broader Community to deliver on its vision and support people development.
Participate as a member of the argenx government relations community, executing relevant evidence generation in support of our strategies.
Upon request, and in partnership with field Market Access and MA&EG, develop and deliver presentations to external stakeholders.
Conduct internal training on HEOR to educate argenx colleagues on the importance of value-evidence and the unique challenges in developing and executing these projects.