Global Product Leader- Cell Therapy, Solid Tumor Franchise

AstraZeneca • Gaithersburg, MD

4d • $251,610 - $377,415

About The Position

Within the AstraZeneca Cell Therapy Unit (CTU), our ambition is to realize the full potential of cell therapy for people living with cancer, immune-mediated and rare diseases around the world. This unit has responsibility for the value chain from discovery through to late-stage development and commercialization. We are rapidly progressing a broad pipeline of cell therapies in collaboration with AstraZeneca’s Therapeutic Area Units.
The Executive Director, Global Product Leader (GPL – Solid Tumor Franchise) - will have overall leadership and accountability for global, cross-functional teams delivering discovery and clinical studies with embedded translational medicine research to establish proof-of-concept data enabling registrational investment strategies. This individual will be accountable for the strategic leadership and execution of clinical development and commercialization plans, aligning prioritization across oncology research units to advance the solid tumor-directed cell therapy pipeline. You will have oncology clinical drug development experience, demonstrated leadership, and be able to critically evaluate the science, clinical data and competitive landscape that underlies each program. You will be able to effectively communicate across a broad range of audiences and have the ability to clearly articulate project-specific strategies and deliverables as it relates to the overall AZ Oncology and Cell Therapy Unit visions.

Requirements

• Graduate degree such as a PharmD, PhD, MD, or an MD/PhD with 10+ years of relevant experience
• Industry experience in designing strategies through all stages of development, coupled with regulatory knowledge
• Strong knowledge and understanding of the Oncology therapeutic area and evolving clinical landscapes
• Demonstrated experience leading and motivating teams in a highly matrixed environment with a proven track record of entrepreneurial decision-making and driving projects to completion
• Proven record of cultivating and managing internal and external collaborations
• Demonstrated success in communicating with and influencing colleagues and senior leaders in various departments

Nice To Haves

• Experience in development of cell therapies
• Experience in early- and late-stage clinical development programs
• Experience developing data and justification leading to successful Ph3 investment decisions
• Experience in the treatment of and/or development of agents for the treatment of prostate cancer, HCC, or pancreatic cancer
• Experience in due diligence (e.g. asset evaluation, assessment of new biomarker and diagnostic tools)
• Experience in US and/or Global commercialization processes

Responsibilities

• Leads one or more Cell Therapy Global Product Teams accountable for strategy and execution of development programs to time and quality; current programs include but are not limited to GPC3, STEAP2, and TCR-T cell therapies
• Holds accountability for the strategy, budget, timeline and execution of discovery and/or clinical studies and the generation of supporting data for investment decisions
• Ensures clinical programs support life cycle management strategies, brand strategy plans, and integrated product development plans from AZ’s emerging portfolio
• Leads and communicates the project development strategy at governance meetings to gain endorsement and to secure funding
• Leads the global product team to effectively communicate and manage risk; responsible for monitoring emerging data and for adjusting strategy when necessary
• Responsible for maintaining a high degree of team effectiveness through collaboration, influence, and, as necessary, coaching and mentoring of cross-functional team members
• Maintains relationships with external investigators to ensure projects are consistent with evolving clinical care and experimental approaches
• Responsible for strong partnership with other GPTs, Therapeutic Area leadership teams, and global functional leads across the business

Benefits

• short-term incentive bonus opportunity
• equity-based long-term incentive program
• retirement contribution
• commission payment eligibility
• qualified retirement program [401(k) plan]
• paid vacation and holidays
• paid leaves
• health benefits including medical, prescription drug, dental, and vision coverage

What This Job Offers

• Job Type: Full-time
• Career Level: Executive