Global Clinical Development Medical Director

AstraZeneca • Gaithersburg, MD

1d • Hybrid

About The Position

AstraZeneca is seeking a clinical research physician to provide medical and scientific leadership for the global development of medicines for infectious disease indications. The role supports clinical development programs from Phase 1 through Phase 3 and offers an opportunity to contribute to the Infectious Disease unit and the development of potential medicines.

The position works across functions and with external scientific specialists, opinion leaders, and study investigators. It includes medical oversight of participant safety, outsourced medical activities, and clinical data, as well as contributions to regulatory documents, publications, and scientific presentations. The employee must be office based at an AstraZeneca site at least three days a week.

Requirements

• Be a fully qualified physician (MD or MD PhD).
• Have clinical experience in pulmonology, infectious disease, or another relevant specialty; pulmonology is preferred.
• Have 1–3 years of experience in clinical drug development, preferably in the pharmaceutical industry.
• Have a strong understanding of clinical trial methodology and experience designing, executing, and interpreting clinical studies, such as medical monitoring, data cleaning, and clinical study report writing.
• Demonstrate excellent teamwork and cross-functional collaboration skills.
• Communicate effectively in clinical team settings.
• Have excellent verbal and written English communication skills, including presentation skills.
• Demonstrate an AI/digital mindset and experience applying AI-enabled and generative AI tools to clinical development activities, such as data analysis, medical writing, and clinical trial operational efficiency.
• Demonstrate high integrity.
• Be office based at an AstraZeneca site at least three days a week.

Nice To Haves

• Additional clinical experience in vaccines and/or monoclonal antibodies.
• Named Investigator on several clinical trials.
• One to three years of pharmaceutical industry knowledge and experience.
• Experience progressing medicines into first-in-human Phase 1, Phase 2 proof-of-principle delivery, and Phase 3 pivotal efficacy studies.
• Experience with translational programs moving from preclinical to first-in-human studies and interpreting immunological assay results.
• A significant and consistent peer-reviewed publication record.

Responsibilities

• Provide medical and scientific leadership in the global development of medicines for infectious disease indications.
• Help design, execute, and interpret clinical trials in one or more development programs from Phase 1 through Phase 3.
• Build relationships with external scientific specialists, opinion leaders, and site investigators.
• Collaborate with Patient Safety, Biometrics, Regulatory Affairs, Clinical Operations, Translational Medicine, and other internal functions.
• Provide medical oversight to support participant safety, including reviewing Adverse Events of Special Interest and Serious Adverse Events and reviewing and writing safety narrative reports.
• Provide medical oversight for medical activities outsourced to third-party vendors.
• Provide expert medical input and write regulatory documents, including interactions and responses with regulatory authorities.
• Analyze and interpret data from ongoing studies and scientific literature.
• Prepare publications and presentations for scientific meetings and congresses.

Benefits

• Short-term incentive bonus opportunity.
• Eligibility to participate in an equity-based long-term incentive program for salaried roles.
• Qualified retirement program (401(k) plan).
• Paid vacation and holidays.
• Paid leaves.
• Health benefits, including medical, prescription drug, dental, and vision coverage.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree