Fall Co-op/Drug Disposition

GSK Internships & Co-ops powered by Atrium • Upper Providence, PA

1d • Onsite

About The Position

The GlaxoSmithKline US Drug Metabolism and Pharmacokinetics (DMPK) organization is responsible for delivery of key DMPK support (in vitro, pharmacokinetic, and bioanalytical) to help drive drug discovery and development programs. Within that structure, the US disposition team is responsible for delivering mechanistic ADME support for both small and large (mAb, oligos) modalities with a focus on high quality. A key remit of DMPK is to characterize ADME (absorption, distribution, metabolism and excretion) properties, predict human pharmacokinetics, assess drug–drug interaction risks, and support safe and effective dose selection for clinical development. As a DMPK intern, you will gain hands-on experience in understanding the ADME profile of drugs, and to conduct in vitro assays to support small and large modalities (ADC, oligos etc).

Requirements

• Pursuing a degree in Biology, Chemistry, Biomedical Engineering, or similar discipline.
• Able to work full-time (35-40 hours/week) throughout the 6 to 12 month co-op (September 2026 - March 2027).
• Must have an active student status and/or within 12 months post-graduation from a BS or MS degree program.
• Post-doctoral candidates are not eligible
• Must successfully pass a drug screen and background check prior to assignment target start date.

Nice To Haves

• Good working knowledge of cell culture techniques, PCR/Taqman technique, media preparation, and laboratory practices.
• Basic understanding of Drug Metabolism, Pharmacokinetic, or Bioanalytical principles.

Responsibilities

• Perform Disposition studies including but not limited to in vitro and ex-vivo mRNA analysis, in various matrices using both manual and automated assay formats.
• Work closely with Disposition staff to investigate/validate/implement in vitro DMPK assays to support global in vitro strategy.
• Assist in optimizing automated assay workflows.
• Analyze, interpret, and present data to DMPK staff.

Benefits

• Relocation stipend for candidates hired for an on-site or hybrid role who reside outside of 50-miles from their assigned work location.
• Competitive hourly pay rate
• Medical benefits
• Fringe benefits
• Overtime pay, in accordance with federal and state requirement.

What This Job Offers

• Job Type: Full-time
• Career Level: Intern
• Education Level: Associate degree
• Number of Employees: 5,001-10,000 employees