Executive Director, Molecular Design Technology (BI&T)

Bristol Myers Squibb • San Diego, MA

1d • Hybrid

About The Position

Bristol Myers Squibb is seeking a leader to serve as Executive Director, Molecular Design Technology—a pivotal role at the intersection of drug discovery science and advanced digital capabilities. This global leader will define and deliver the technology strategy and capabilities that enable modality-agnostic molecular design and optimization across the R&D pipeline, in deep partnership with Research leadership spanning small molecules, biologics, and emerging modalities. The scope is explicitly focused on modality-agnostic design and optimization and excludes target identification and validation. Reporting to the Vice President of Research Business Insights & Technology (BI&T), this individual will accelerate the shift from technology layered onto traditional workflows to computationally based, AI-driven ways of working. In partnership with research scientists, Computational Sciences leaders, and BMS’s R&D Data organization, the role will advance a multi-year vision for integrated AI, data, and systems—ensuring design data and knowledge flow seamlessly across Research and into Development. As a member of the BI&T leadership team, this leader will serve as a trusted partner to Research leaders to align priorities, roadmaps, and adoption across the organization.

Requirements

• Ph.D. in Chemistry, Computational Chemistry, Structural Biology, Bioinformatics, or related field
• 15+ years of experience in drug discovery, with:
• Deep experience in molecular design (small and/or large molecule)
• 10+ years operating at the intersection of science and technology/IT
• Proven track record of leading technology-enabled transformation in a pharmaceutical or biotech R&D environment
• Demonstrated experience implementing or scaling: Molecular modeling platforms AI/ML-driven drug design capabilities Integrated scientific data environments
• Strong understanding of end-to-end drug discovery workflows, particularly within design and optimization phases
• Experience deploying GenAI and agentic capabilities into scientist workflows, and driving DMTA cycle-time reduction or comparable closed-loop optimization
• Experience operating at Director/Senior Director level or above, with readiness for Executive Director scope
• Exceptional communication skills, with the ability to translate complex technical concepts into clear, actionable narratives
• Proven ability to lead organizational change within scientific environments, driving adoption and behavioral shifts
• High degree of emotional intelligence and credibility with senior scientists
• Ability to operate effectively in ambiguous, evolving environments, bringing structure and clarity
• Commitment to building an inclusive, high-performing culture grounded in trust and accountability

Nice To Haves

• Experience driving AI-enabled molecular design transformation at scale
• Background bridging bench science, computational methods, and enterprise platforms
• Demonstrated success integrating fragmented tool ecosystems into unified platforms
• Credibility with both internal R&D leaders and external innovation partners

Responsibilities

• Own the end-to-end technology strategy and roadmap for molecular design and optimization across modalities (small molecule, biologics, and emerging).
• Align priorities and drive delivery in close partnership with Discovery Biology, Medicinal Chemistry, Computational Sciences, and lab leadership.
• Select and scale core platforms and tools for structure-based design, modeling & simulation, AI/generative design, and design-workflow visualization.
• Architect and deliver an integrated design ecosystem (interoperable tools, datasets, and workflows) to reduce fragmentation and improve usability.
• Deliver measurable outcomes (e.g., DMTA cycle-time reduction; closed-loop optimization) through AI/ML, generative, and agentic capabilities.
• Own compound and entity registration systems and workflows, partnering with the R&D Data organization on the registered-entity data product.
• Ensure operational excellence (reliability, performance, support, and governance) for design platforms and integrated applications.
• Connect upstream Research with downstream Development (e.g., CMC and Manufacturing IT) so Development learnings flow back into design decisions.
• Build and lead a high-performing organization (talent, culture, performance) and manage external partnerships (vendors, startups, academic collaborators).

Benefits

• Medical, pharmacy, dental, and vision care.
• BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
• Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
• Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
• Unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
• Summer hours flexibility (for eligible employees)

What This Job Offers

• Job Type: Full-time
• Career Level: Executive
• Education Level: Ph.D. or professional degree