Executive Director, Global Product Team Lead (GPTL) – UPLIZNA

Amgen • Thousand Oaks, CA

34d • $334,190 - $452,140

About The Position

At Amgen, if you feel like you are a part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

What you will do
Let’s do this. Let’s change the world. In this vital role, you will serve as the “CEO of the molecule,” driving strategy, execution, and value realization for UPLIZNA. The Executive Director, Global Product Team Lead (GPTL) will be the single point of accountability for the product, responsible for leading cross-functional teams in the design, integration, and execution of strategy across the product lifecycle—from development through launch and in-line optimization. The GPTL has enterprise accountability for end-to-end product strategy, prioritization, and delivery, ensuring integrated decision-making, disciplined governance, and maximization of asset value. This role is central to driving strategic alignment, accelerating decision-making, managing risk, and ensuring execution against key milestones while maintaining a patient-first mindset. The Executive Director, GPTL is a global role requiring extensive cross-functional leadership, communication, and managerial capabilities across internal, external, and regional stakeholders.

Requirements

• Doctorate degree and 6 years of product strategy experience; OR Master’s degree and 10 years of product strategy experience; OR Bachelor’s degree and 12 years of product strategy experience
• 6 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation of resources

Nice To Haves

• 10+ years of industry experience within biotechnology, pharmaceutical, or healthcare-related fields
• Proven experience leading complex, global, cross-functional product teams
• Deep understanding of development-to-commercial product lifecycles
• Enterprise decision-making and governance leadership experience
• Advanced understanding of key functions including Research, Pre-Clinical, Clinical Development, Regulatory, Manufacturing, Medical Affairs, Market Access, and Commercial
• Business and financial acumen, with the ability to connect technical program drivers to commercial value and enterprise strategy
• Executive communication and interpersonal skills, with the ability to influence and align senior stakeholders
• Ability to synthesize complex information into clear strategic recommendations and governance decisions
• Executive foresight to anticipate disease-area evolution, competitive dynamics, and emerging opportunities
• Problem-solving and decision-making capabilities, balancing speed, rigor, and organizational alignment
• Integrator who connects people, ideas, functions, and priorities to maximize enterprise impact
• Ability to coach, motivate, and develop talent while creating high-performing teams
• Ability to operate credibly and effectively with senior executives across R&D and Commercial organizations

Responsibilities

• Product Strategy & Value Maximization: Own the integrated product strategy and lifecycle roadmap for UPLIZNA, ensuring alignment of scientific, regulatory, medical, access, operational, and commercial priorities. Define strategic options, assess tradeoffs, and drive decisions that maximize patient impact and long-term asset value across indications and geographies. Integrate portfolio context, competitive intelligence, and disease-area insights into strategic recommendations.
• Cross-Functional Leadership & Execution: Lead the global Product Team and serve as the single point of integration across Development, Medical, Regulatory, Value & Access, Operations, Manufacturing, and Commercial functions. Drive accountability for execution, proactively identify risks, remove decision bottlenecks, and ensure alignment against key milestones and objectives. Establish effective team culture, operating principles, decision rights, and escalation pathways.
• Governance & Enterprise Decision-Making: Lead engagement with Therapeutic Area Governance, Product Governance, and portfolio forums, ensuring high-quality decision-making and organizational alignment. Present strategic recommendations, risks, financial implications, and tradeoffs to senior leadership and governance bodies. Ensure timely escalation and resolution of issues that materially impact value, timelines, or risk.
• Product Planning & Resource Management: Own key enterprise deliverables, including the Target Product Profile, Integrated Product Strategy, lifecycle roadmap, and evidence generation plans. Partner with cross-functional leaders to manage financial planning, forecasting, resource allocation, and investment decisions that support product objectives.
• Commercial Integration & Lifecycle Leadership: Partner closely with the Global Marketing Lead to ensure alignment between product strategy and commercial strategy. Drive lifecycle management and Patient Impact Expansion opportunities while ensuring product decisions are translated into meaningful commercial and patient outcomes.
• Leadership & Culture: Serve as the enterprise steward of the product, balancing near-term execution with long-term portfolio priorities. Foster a culture of innovation, accountability, inclusion, and continuous improvement while developing and mentoring team members. Model Amgen's values—Integrate, Adapt, Inspire, and Accelerate—in all aspects of leadership.

Benefits

• Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans and bi-annual company-wide shutdowns
• Flexible work models where possible.

What This Job Offers

• Job Type: Full-time
• Career Level: Executive
• Education Level: Ph.D. or professional degree