Executive Director, Cell Therapy Global Supply Chain Planning

AstraZenecaGaithersburg, MD
$225,000 - $335,000Hybrid

About The Position

AstraZeneca is building one of the industry’s most ambitious Cell Therapy portfolios, spanning autologous, allogeneic, and in vivo modalities. As the business evolves from clinical-stage operations to global commercial scale, we are seeking a senior leader to build the planning capability that will support reliable patient supply, successful launches, and long-term growth. The Executive Director, Cell Therapy Global Supply Chain Planning reports into the Vice President, Cell Therapy Global Supply Chain and will lead the transformation of planning for the Cell Therapy business. You will shape the operating model, build the organization and capabilities, and establish the governance, processes, and systems needed to support a complex, global, multi-product portfolio. This is a highly visible leadership role with broad enterprise impact owning the decision architecture that aligns assumptions, risks, priorities, and tradeoffs across the enterprise to enable effective executive decision making. You will work across Commercial, Clinical, Finance, Manufacturing, Quality, Process Development, Regulatory, CMC, and Supply Chain to create a modern, integrated planning function aligned to AstraZeneca’s long-term Cell Therapy ambition.

Requirements

  • Bachelor’s degree in Supply Chain, Operations, Engineering, Life Sciences, Business Administration, or a related field
  • 16+ years of relevant experience, or 14+ years with an MS/MBA, or 12+ years with a PhD
  • Deep expertise in supply planning, capacity planning, integrated business planning, inventory strategy, and planning governance
  • Demonstrated experience leading planning transformation and evolving operating models from clinical-stage, early-launch, or emerging business environments to commercial scale
  • Experience scaling supply chains through commercial growth, geographic expansion, and organizational change
  • Experience in biopharma, biotech, advanced therapies, or other highly regulated and complex supply environments
  • Demonstrated success leading across internal manufacturing and external partner networks
  • Experience implementing or advancing planning capabilities such as OMP, Kinaxis, o9, or equivalent platforms
  • Proven ability to build, lead, and develop high-performing teams in complex, matrixed organizations
  • Strong strategic, analytical, communication, and stakeholder leadership skills

Nice To Haves

  • Advanced degree such as MBA, MS, or PhD
  • Experience in cell therapy, gene therapy, oncology supply chains, or personalized medicine
  • Experience in highly constrained, time-sensitive, or patient-specific supply environments

Responsibilities

  • Lead the end-to-end planning function for Cell Therapy, connecting commercial demand, clinical enrollment, patient flow, supply planning, inventory strategy, materials planning, capacity planning, and financial assumptions into a unified planning framework that is appropriate to patient-specific therapies
  • Lead the transformation of the planning operating model from a clinical-stage environment to a scalable global commercial capability, including organization design, governance, decision rights, processes, and ways of working
  • Build the planning capabilities needed to support growth, including launch readiness, market expansion, increasing product and geographic complexity, and volume growth across the portfolio
  • Lead S&OP/IBP and S&OE as enterprise decision-making forums, establishing the planning and governance architecture that aligns cross-functional assumptions, risks, priorities, and scenarios, and enables timely executive decisions across service, cost, cash, risk, and growth
  • Drive cross-functional executive alignment across Commercial, Clinical, Finance, Manufacturing, Quality, Process Development, Regulatory, CMC, and Supply Chain, ensuring assumptions, constraints, priorities, and trade-offs are transparent, reconciled, and translated into clear enterprise decisions
  • Develop differentiated planning strategies across autologous, allogeneic, and in vivo modalities, as well as across clinical and commercial supply models, product lifecycle stages, and markets
  • Lead global network and capacity planning across internal manufacturing sites and external partners, including capacity allocation, slot management, and supply prioritization across products, programs, and geographies, and partner with the Network Strategy team to align long-range planning, network expansion, and future-state supply network decisions with business growth and portfolio needs
  • Provide integrated decision making and planning of Supply Chain within CMC program governance, ensuring supply, logistics, and capacity constraints are translated into clear direction and integrated supply plans
  • Oversee the planning architecture across Plan-to-Deliver, from demand translation through supply planning, detailed scheduling, and execution handoffs to drive planning excellence through patient outcomes such as vein-to-vein time and slot availability
  • Lead scenario planning and planning risk management, helping the business anticipate and respond to supply, capacity, logistics, and launch risks
  • Drive future state digital planning ambition, including SAP maturity, advanced planning tools, scheduling and slot management solutions, AI/ML-driven demand sensing, autonomous planning capabilities, planning data standards, and decision-support analytics
  • Build and lead a high-performing team, developing talent and strengthening planning capability across the organization

Benefits

  • We balance the expectation of being in the office while respecting individual flexibility.
  • The annual base salary for this position ranges from $225,000 to $335,000.
  • If hired, employee will be in an “at-will position” and we reserve the right to modify base salary (and any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
  • Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees.
  • In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics.
  • If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
  • At AstraZeneca, we’re dedicated to being a Great Place to Work.
  • Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit.
  • To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges.
  • There is no better place to make a difference in medicine, patients, and society.
  • An inclusive culture where you will connect different thinking to generate new and valuable opportunities.
  • Where you will find a commitment to lifelong learning, growth and development for all.
  • Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients.
  • Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking.
  • We’re curious about science and the advancement of knowledge.
  • We find creative ways to approach new challenges.
  • We’re driven to make the right choices and be accountable for our actions.
  • As an organisation centred around what makes us human, we put a big focus on people.
  • Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab.
  • Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential.
  • Here, you’ll do work that has the potential to change your life and improve countless others.
  • And, together with your team, you’ll shape a culture that unites and inspires us every day.
  • This is your life at AstraZeneca.
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