Engineer I, Process Development, Pilot Scale Operations

ModernaTX • Norwood, MA

3h • Onsite

About The Position

The Pilot Scale Operations team is seeking a highly skilled and motivated full-time Engineer I to support Formulations (Lipid Nanoparticle and Drug Product) pilot-scale production. Qualified candidates will have relevant academic or industry experience in solution preparation, lipid nanoparticle, sterile fill/finish and/or tangential flow filtration experience, and an understanding of scaling and technology transfer of these unit operations. A successful candidate should have exposure to large and small-scale equipment maintenance and troubleshooting; as well as authoring and updating equipment specific SOPs. This position will require excellent communication and organizational skills, as well as a focus on operational excellence and process optimization. A successful candidate must demonstrate the independent drive and collaborative spirit to operate in a dynamic, fast-paced environment.

Requirements

• Demonstrated success in bioprocess development, technical problem solving, and technology transfer are essential
• BS/BA (required) or MS in Chemistry, Systems, Biomedical or Chemical Engineering, or closely related field with 0-2 years related experience
• Ability to multi-task in relentless pursuit of successful outcomes
• Exceptional written and oral communication

Nice To Haves

• Hands-on experience with fermentation, enzymatic reaction, chromatography and/or tangential flow filtration experience is preferred
• Relevant academic or industry experience in solution preparation, lipid nanoparticle, sterile fill/finish and/or tangential flow filtration experience
• Understanding of scaling and technology transfer of these unit operations
• Exposure to large and small-scale equipment maintenance and troubleshooting
• Authoring and updating equipment specific SOPs

Responsibilities

• Be the receiving unit for technology transfer from Moderna’s Process Development teams, focusing on Formulations sciences, including drug formulation/delivery development
• Assist other development scientists / engineers in defining process development and scale-up strategy, and implementing process control strategies
• Operate, maintain, and troubleshoot custom equipment used to manufacture Formulations batches
• Characterize product attributes through collaboration with analytical and technical teams
• Demonstrate and implement lab best practices
• Update and write standard operating procedure (SOPs) associated with production as needed
• Practice safe work habits and adhere to Moderna safety procedures and guidelines
• Adhere to documented waste handling procedures to respect environmental regulations

Benefits

• Competitive healthcare, plus voluntary benefit programs to support your unique needs
• A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
• Family planning benefits, including fertility, adoption, and surrogacy support
• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
• Savings and investments to help you plan for the future
• Location-specific perks and extras

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Associate degree