About The Position

This role performs experiments to support downstream process development activities for viral vector manufacturing. The work includes operating and supporting downstream processing equipment and activities, documenting process parameters and analytical data, managing project supplies, analyzing experimental results, and communicating findings to the project team. The position also involves writing technical documents and maintaining primary work records in electronic notebooks. The position is full-time, Monday through Friday, from 8:00 a.m. to 5:00 p.m. Candidates living within commuting distance of Spring House, Pennsylvania, are encouraged to apply.

Requirements

  • Bachelor’s degree in life sciences or a related scientific discipline and at least 2 years of direct downstream experience, or a master’s degree and 0–2 years of experience.
  • Hands-on experience purifying proteins or biologics.
  • Broad knowledge of chromatography techniques and purification process development.
  • Ability to document work accurately in notebooks, protocols, reports, and electronic systems.
  • Strong scientific, organizational, and communication skills, with attention to detail.
  • Authorization to work indefinitely in the United States without restriction or sponsorship.

Nice To Haves

  • Knowledge of GMP and experience working in a regulated laboratory environment.
  • Previous viral vector experience.
  • Experience transferring a purification process to clinical and commercial GMP manufacturing.

Responsibilities

  • Execute Tangential Flow Filtration (TFF) operations, including system setup, processing, monitoring, and documentation.
  • Support downstream processing activities, including clarification, nuclease treatment, filter screening, sterile filtration, and AEX chromatography using both manual and AKTA-based operations.
  • Perform and support column-packing activities.
  • Capture, maintain, and document process parameters and analytical data in the project Master Data File.
  • Assist with inventory management and procurement of project supplies to ensure material availability and operational continuity.
  • Record and analyze experimental data and verify data integrity and accuracy.
  • Report and summarize findings to the project team.
  • Write technical documents and maintain main work records in electronic notebooks.

Benefits

  • Comprehensive medical coverage
  • Dental insurance
  • Vision options
  • Life insurance
  • Disability insurance
  • 401(k) with company match
  • Paid vacation
  • Paid holidays
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