Downstream Process Development Engineer - LNP
About The Position
The Downstream Process Development Engineer performs lab-scale downstream processing of vaccine adjuvant and Lipid Nanoparticle (LNP) products and process intermediates. The role also performs biochemical and analytical assays on products, intermediates, and related experimental samples; prepares solutions and reagents; and sets up process equipment for lab-scale experiments. Experimental records and results must be maintained in accordance with good manufacturing practices (GMP). The position is full-time and permanent, Monday through Friday, 8:00 a.m. to 5:00 p.m., with overtime as needed. On-site work is expected, and candidates within commuting distance of West Point, Pennsylvania, are encouraged to apply.
Requirements
- Bachelor's degree in Engineering and 8 or more years of industry experience, or a Master's degree in Engineering and 6 or more years of industry experience, or a Ph.D. in Engineering and 2 or more years of industry experience.
- Authorization to work indefinitely in the United States without restriction or sponsorship.
- Experience with adjuvant and LNP process unit operations, including extrusion, tee-mixing, Multi-Inlet-Vortex-Mixing (MIVM), homogenization/microfluidization, filtration, and tangential flow filtration (TFF).
- Scale-up experience related to liposome and LNP formation unit operations, including extrusion, tee-mixing, and microfluidization/homogenization.
- Experience handling potent compound lipids (OEB4 and OEB5) and working in isolators and Ventilated Booth Enclosures (VBEs).
Nice To Haves
- Strong computer, scientific, and organizational skills.
- Excellent oral and written communication skills and attention to detail.
- Ability to work independently and as part of a team, with self-motivation, adaptability, and a positive attitude.
- Ability to learn new techniques, perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies.
- Proven ability to work independently in a hands-on laboratory setting.
Responsibilities
- Perform lab-scale downstream processing of vaccine adjuvant and LNP products and process intermediates.
- Perform biochemical and analytical assays on vaccine adjuvant and LNP products, process intermediates, and related experimental samples.
- Prepare solutions and reagents.
- Set up process equipment for lab-scale experiments.
- Maintain records and experimental results in accordance with GMP.
Benefits
- Comprehensive medical coverage.
- Dental and vision options.
- Life and disability insurance.
- 401(k) with company match.
- Paid vacation and holidays.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
