About The Position

We are sharing a specialised part-time consulting opportunity for DNA nanotechnology researchers with advanced expertise in structural nucleic-acid design, molecular self-assembly, strand-displacement systems, and scientific problem development. This role supports an advanced AI research initiative focused on strengthening expert-level reasoning in structural DNA nanotechnology. Selected professionals will author challenging technical problems, review peer-developed tasks for scientific accuracy and difficulty, and evaluate AI-generated solutions using rigorous standards grounded in current research practice.

Requirements

  • Advanced research experience in DNA nanotechnology, nucleic-acid engineering, bioengineering, biophysics, chemistry, or a closely related field
  • Hands-on expertise in DNA origami, structural nucleic-acid design, molecular self-assembly, or strand-displacement systems
  • Strong understanding of sequence design, structural stability, and nucleic-acid interactions
  • Experience developing, analysing, or validating complex DNA nanostructures
  • Ability to create and solve technically challenging scientific problems
  • Excellent scientific writing and meticulous attention to detail
  • Experience reviewing research, technical analyses, or advanced academic work
  • A PhD in chemistry, bioengineering, biophysics, molecular engineering, nanotechnology, or a related discipline is highly relevant
  • Equivalent research experience focused on DNA or nucleic-acid nanotechnology may also be considered
  • Postdoctoral, university, national-laboratory, or industry research experience may strengthen an application
  • Publications or substantial technical contributions in structural DNA nanotechnology are valuable

Nice To Haves

  • Experience with DNA origami design and experimental validation
  • Familiarity with caDNAno, oxDNA, NUPACK, or comparable design and simulation tools
  • Background in strand-displacement circuits or dynamic nucleic-acid systems
  • Expertise in molecular self-assembly and nanoscale structural engineering
  • Experience with sequence optimisation, thermodynamic modelling, or structural simulation
  • Familiarity with laboratory methods used to assemble and characterise DNA nanostructures
  • Experience teaching, grading, peer reviewing, or developing advanced scientific problems
  • Previous exposure to AI evaluation, rubric development, or technical training-data projects

Responsibilities

  • Design expert-level problems involving DNA origami, nucleic-acid nanostructures, strand-displacement systems, and sequence or structure design
  • Create tasks requiring multi-step scientific reasoning, quantitative analysis, and technically defensible conclusions
  • Develop clear problem statements, assumptions, constraints, and expected outcomes
  • Prepare accurate reference solutions and supporting scientific explanations
  • Ensure tasks reflect genuine research-level difficulty
  • Assess DNA and nucleic-acid structures for design feasibility, stability, and intended function
  • Review sequence-level considerations including complementarity, strand interactions, and secondary structure
  • Evaluate molecular self-assembly pathways and strand-displacement mechanisms
  • Identify design conflicts, unsupported assumptions, and structural inconsistencies
  • Apply relevant thermodynamic and biophysical principles to proposed solutions
  • Review problems and reference answers authored by other specialists
  • Assess clarity, originality, technical difficulty, and scientific correctness
  • Verify assumptions, calculations, sequence logic, and design methodology
  • Identify ambiguity, incomplete specifications, and unintended solution shortcuts
  • Recommend revisions that improve scientific rigour and evaluation reliability
  • Review and compare AI-generated solutions to advanced DNA nanotechnology problems
  • Assess scientific reasoning, design decisions, calculations, and final conclusions
  • Identify conceptual errors, infeasible structures, incorrect sequence logic, and unsupported claims
  • Assign Accept, Revise, or Reject outcomes with detailed written rationale
  • Explain technical failures clearly and recommend appropriate corrections

Benefits

  • Flexible remote work
  • Competitive hourly compensation
  • Weekly payments via Stripe or Wise
  • Projects may be extended, shortened, or adjusted depending on scope and performance

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What This Job Offers

Job Type

Part-time

Career Level

Senior

Education Level

Ph.D. or professional degree

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