Director - Tax

Caris Life Sciences•Irving, TX

About The Position

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives. We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do. But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose. Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins. Position Summary The Director of Tax must be a “hands-on” self-starter who can function as the in-house expert and facilitator on all things tax related. The ideal candidate is a highly accountable, detail-oriented leader with strong foundational GAAP knowledge and a demonstrated control mindset. This person should also have the ability to create strong relationships with key internal and external stakeholders and should possess a combination of strong technical knowledge, leadership skills, significant experience with income tax provisions, income tax compliance, indirect taxes.

Requirements

Bachelor’s degree in accounting or equivalent.
Minimum ten years of experience with a combination of Big Four and a publicly traded company.
Active CPA license.

Nice To Haves

Diagnostic industry experience.
Master’s degree.
Proven track record of building and maintaining strong control environments, including SOX compliance and audit interaction.
Demonstrated ability to operate with high ownership, accountability, and responsiveness in a fast-paced environment.

Responsibilities

Ensure technical accuracy and defensibility of all ASC 740 positions, including proper distinction between errors and changes in estimate under ASC 250, and clear documentation of judgments.
Own full lifecycle of tax provision and compliance, including rigorous provision-to-return analysis with clear explanations of all variances.
Oversee and manage various tax-related filings and related audits, including property taxes, payroll taxes, etc.
Manage special projects such as tax planning, sales/use/withholding tax assistance as needed.
Design, implement, and enforce strong internal controls, including high-quality tax supporting schedules and balance sheet reconciliations.
Act as a hands-on reviewer and control owner, ensuring all reconciliations, journal entries, and supporting schedules meet a high standard of precision, clarity, and audit readiness.
Review annual statutory tax provisions and the financial statements of foreign subsidiaries as prepared under local GAAP.
Establish clear expectations for responsiveness, communication, and timeliness across the tax function, including prompt email follow-up and cross-functional coordination.