Director, Quantitative Clinical Pharmacology
About The Position
As the Director of Quantitative Clinical Pharmacology, you will play a pivotal role in advancing BioNTech’s innovative drug development pipeline. Your expertise in population pharmacokinetics (PK), exposure-response (ER), and pharmacokinetic/pharmacodynamic (PK/PD) modeling will directly contribute to the development of new treatments for patients worldwide. In this position, you will lead program-level pharmacometrics strategies, foster cross-functional collaboration to drive decision-making, and support regulatory submissions such as IND and NDA/BLA filings. You will also serve as a mentor within the department while shaping best practices in quantitative modeling and analysis.
Requirements
- Ph.D., Pharm.D., or M.D. in pharmaceutics, pharmacokinetics, or related fields; M.S. with extensive relevant experience also considered
- Minimum 8 years in biotechnology or pharmaceuticals with hands-on expertise in population PK/PD modeling and regulatory submissions
- Proficiency in NONMEM, R, Phoenix WinNonlin, MATLAB; strong documentation skills for delivering high-quality analyses independently
- Experience overseeing, or other applicable experience with external pharmacometrics vendors and managing modeling and simulation deliverables across multiple programs
- Proven ability to lead matrixed teams effectively; excellent communication skills for conveying complex concepts at all levels
- Experience in oncology; deep understanding of translational research principles
Responsibilities
- Lead hands-on and supervisory population PK, ER, and PK/PD modeling activities using software such as NONMEM, R, Phoenix WinNonlin, or MATLAB
- Drive translational modeling to connect preclinical data with clinical outcomes, supporting dose optimization and go/no-go decisions
- Provide strategic oversight and leadership of external pharmacometrics vendor partnerships, including scope definition, study oversight, quality review, budget management, and delivery of modeling and simulation activities
- Provide quantitative insights for regulatory documents and serve as BioNTech’s representative during Health Authority engagements worldwide
- Influence program strategy through pharmacometric leadership across cross-functional teams
- Recruit, mentor, and develop junior staff while contributing to departmental best practices
Benefits
- competitive remuneration packages
- annual bonus & equity
- benefits
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What This Job Offers
Job Type
Full-time
Career Level
Director
Education Level
Ph.D. or professional degree
