Director (Principal Scientist) - Precision Medicine - Outcomes Research

MSD•North Wales, PA

1d•$190,800 - $300,300•Hybrid

About The Position

This position resides within our company Value and Implementation (V&I) Oncology organization, which leads the execution of value evidence plan and delivery of strategic real-world evidence (RWE) capabilities to inform healthcare decision making. Under the guidance of a senior leader, the Principal Scientist will provide US and ex-US outcomes research support for Oncology programs focusing on Precision Medicine.

Requirements

Doctoral degree in relevant discipline (health services research, outcomes research, epidemiology, public health, health economics, pharmacoeconomics, pharmacy administration)
Expertise in translational oncology/molecular epidemiology, observational study best practices, fitness-for-use, real world evidence frameworks, and global guidelines on the conduct of observational research.
Four or more years of experience with a post degree.
Biobank
Biomarker Development
Biomarkers
Clinical Analytics
Clinical Development
Clinical Research
Clinical Sciences
Conference Presentations
Data Management
Epidemiology
Observational Studies
Personalized Medicine
Real World Data
Researching
Research Management
Research Programs
Research Protocols
Scientific Literacy
Scientific Presentations
Scientific Research
Scientific Writing
Stakeholder Relationship Management
Strategic Planning
Study Design

Nice To Haves

Expertise in Real-world evidence generation, advanced biostatistics and computational biology.
Prior experience in digital pathology related analytics.
Laboratory experience to understand how tissue is processed, including sample logistics, biobanking, pathology, and QA/QC considerations.
Expertise in diagnostic test modalities (e.g., IHC, ISH, PCR, NGS, digital pathology, multiplex), Assay sensitivity/specificity.
A track record of scientific presentations and publications.
Experience in Oncology related outcome research and/or epidemiology.

Responsibilities

Provide leadership and consultation on evidence generation methods for translational oncology/molecular epidemiology studies to support access, value demonstration, and medical implementation. Precision Medicine studies the candidate will lead include those on biomarkers with approved diagnostics across multiple tumors, studies involving tissue processing or acquisition, and studies on emerging biomarkers without approved diagnostics.
Provide subject matter expertise in Outcomes research and precision medicine to internal and external stakeholders, including precision medicine integrated value and implementation team and related functions.
Design and execute observational and real-world studies in support of access, value demonstration, and medical implementation.
Inform and contribute to the value evidence plan and associated studies which demonstrate clinical, economic, and patient-centered value.
Support the implementation of the RWE capability maturity model for global excellence in RWE generation, in partnership with local RWE experts and stakeholders.
Communicate findings from the research to relevant internal and external audiences, including supporting the development of communication resources.
Collaborate with internal stakeholders to ensure research priorities and plans are aligned.
Communicate with relevant external audiences including health care providers, health systems, HTAs, patient organizations, and others.
Design and execute outcome research studies, in collaboration with scientific leaders, patient organizations, academic medical centers, health systems, research organizations, database holders, and others.
Prepare outcome research protocols, statistical analysis plans, and clinical study reports.
Communicate findings at scientific conferences, publications, dossiers, and by other means.
Maintain awareness of scientific developments in the field.