Director or Senior Director, Translational Medicine Lead

Kymera Therapeutics•Watertown, MA

3d•$195,000 - $330,000

About The Position

Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years.

Requirements

PhD +8-10 years of experience in translational medicine/ science within the biotech/pharmaceutical industry
Demonstrated success leading translational medicine efforts for immunology and /or respiratory drug development programs
Demonstrated experience delivering high quality clinical biomarker data to inform decisions and development strategy
Track record of working effectively with CROs to design and execute studies
Demonstrated innovation in applying novel translational approaches to drug development
Strong leadership, communication, and cross-functional collaboration skills

Responsibilities

Serves as an Immunology Translational Medicine Program Lead on cross-functional project team(s) and develops translational medicine and biomarker strategies to support early and late phase clinical trials
Collaborates with Medicine team to develop clinical trials in appropriate patient populations
In partnership with the Translational Medicine Biomarker Operations team and Clinical Operations team oversees seamless implementation of translational assays in the clinic
Develops and validates clinical assays at outsourced partner laboratories using multiple assay technology platforms (e.g., cell-based assays, molecular-based assays, single or multiplexed immunoassays, flow cytometry and/or imaging technologies)
Ability to review and interpret data /results from multiple types of biomarker assays and integrate findings
Presents translational medicine data packages internally and externally as required
Effectively coordinates with Translational Medicine Biomarker Operations team to manage external collaborations with academic partners and CROs to deliver results on time and on budget
Review and author translational medicine sections of clinical documentation, including clinical protocols, study reports, consent forms; abstracts and/or manuscripts and regulatory documents (e.g. IND, IB etc.)
Builds biomarker knowledge base in the context of disease outcomes to contribute to advancement of clinical stage programs
Monitors developing biomarker approaches and incorporate novel technologies in support of ongoing and new clinical programs
Interfaces effectively with Translational Medicine Head to ensure alignment on topics