Director Medical Information

Amylyx Pharmaceuticals•Cambridge, MA

10d•$211,000 - $237,000•Remote

About The Position

The Director, Medical Information will serve as the functional lead for Amylyx’s global medical information function, reporting to the Director, Medical Affairs. The initial focus of the role will be establishing and scaling U.S. Medical Information capabilities in support of launch readiness, with the expectation that the function and operating model will evolve to support broader global needs over time. The Director will define and execute the global Medical Information strategy and operating model. Responsibilities include content strategy, inquiry management, vendor and contact center oversight, systems, quality, reporting, and insights generation. The Director will ensure external stakeholders receive accurate, balanced, evidence-based, and compliant scientific information while generating actionable insights that inform Medical Affairs strategy and cross-functional decision-making. The role will partner closely with Medical Affairs, Field Medical, Scientific Communications, Clinical Development, Pharmacovigilance/Drug Safety, Quality, Commercial, Market Access, Patient Support, and other functions to support compliant scientific exchange and launch readiness.

Requirements

Advanced scientific or clinical degree required, such as (e.g., pharmD, PhD).
5 + years of relevant experience in the biotechnology or pharmaceutical industry, including substantial experience in Medical Information, Medical Affairs, or a related scientific function.
Direct experience leading Medical Information strategy, content development, inquiry management, vendor/contact center oversight, systems, quality monitoring, reporting, and launch planning.
Strong understanding of regulatory, compliance, pharmacovigilance, and product complaint requirements governing scientific exchange with healthcare professionals, patients, caregivers, and other external stakeholders.
Excellent written and verbal communication skills, with the ability to interpret complex scientific information and deliver accurate, balanced, evidence-based, and appropriately tailored responses.
Demonstrated cross-functional leadership, stakeholder management, and project management skills, including the ability to influence without direct authority, manage competing priorities, and operate effectively in a dynamic environment.
Experience developing and communicating Medical Information metrics, KPIs, and actionable insights to inform business decisions.
Proficiency with Medical Information systems, document management platforms, Microsoft Office, Veeva Vault, Veeva CRM, Adobe Acrobat, or similar technology platforms.

Nice To Haves

Experience supporting product launches, launch readiness, lifecycle management, and the evolution of Medical Information capabilities across products, regions, or therapeutic areas.
Experience in rare disease, endocrinology, metabolic disease, neurology, or other relevant therapeutic areas.
Demonstrated people leadership experience, including the ability to recruit, develop, coach, and lead high-performing teams, vendors, and cross-functional partners.

Responsibilities

Build and scale Amylyx's Medical Information function, including strategy, operating model, capabilities, infrastructure, and roadmap, with an initial focus on U.S. launch readiness and a foundation for future global expansion.
Oversee the development, approval, maintenance, and deployment of Medical Information content, including standard response letters, FAQs, scripted responses, templates, tailored responses for unsolicited inquiries, AMCP dossiers, and other payer-facing scientific resources.
Select and manage Medical Information vendors and contact center partners, including training, performance objectives, KPIs, quality monitoring, corrective actions, budget tracking, and continuous improvement.
Ensure Medical Information responses are scientifically accurate, balanced, evidence-based, and compliant with applicable regulations, SOPs, and industry standards.
Represent Medical Affairs in Medical, Legal, and Regulatory (MLR) review processes and other cross-functional review forums as appropriate.
Monitor inquiry trends, metrics, and customer insights to identify unmet content needs and generate actionable insights for Medical Affairs and cross-functional stakeholders.
Support Medical Affairs activities related to scientific conferences and medical congresses, including content preparation, congress inquiry management, insight gathering, and scientific exchange support as appropriate.
Partner cross-functionally with Medical Affairs, Field Medical, Scientific Communications, Clinical Development, Pharmacovigilance/Drug Safety, Quality, Commercial, Market Access, Patient Support, and other teams to support compliant scientific exchange, launch readiness, operational excellence, and appropriate escalation of inquiries, adverse events, and product quality complaints.