Director, Medical Affairs – Oncology (Contractor)

pmvpharma • Princeton, NJ

3d • Hybrid

About The Position

PMV Pharma is a precision oncology company focused on the discovery and development of small molecule therapies targeting p53, a well-characterized tumor suppressor protein mutated in approximately half of all cancers. Leveraging deep scientific expertise and a differentiated approach to reactivating p53, PMV is advancing a pipeline of novel therapies designed to address significant unmet medical needs. The company operates with a lean, highly collaborative team and is progressing toward key clinical and regulatory milestones in support of future commercialization. The Director, Medical Affairs (Contractor) is currently a project-based role responsible for supporting the development and execution of key Medical Affairs initiatives for the oncology portfolio. This role is engaged to deliver high-priority strategic and operational outputs aligned with clinical, regulatory, and pre-commercial milestones.

Requirements

• MD, PhD, or PharmD with significant experience in Oncology Medical Affairs
• ~8–10+ years in biotech/pharmaceutical industry, including Medical Affairs leadership or equivalent strategic experience
• Proven ability to independently deliver Medical Affairs strategy and execution in a fast-paced environment
• Strong understanding of regulatory requirements and scientific communication standards
• Demonstrated success in cross-functional collaboration and external stakeholder engagement
• Excellent communication and analytical skills
• Ability to operate with minimal oversight and rapid ramp-up

Nice To Haves

• Willingness to travel (~20%)

Responsibilities

• Drive execution of defined components of the Global Medical Affairs Plan
• Partner with cross-functional teams (Clinical Development, Regulatory, Market Access, Commercial) to ensure aligned scientific and communication strategies
• Develop and disseminate scientific and medical materials for healthcare providers, payors, and other stakeholders
• Support advisory board planning and execution aligned with program objectives
• Contribute to KOL engagement strategy and external relationship management
• Monitor and synthesize competitive landscape, clinical data, and scientific trends to inform tactical decision-making
• Provide medical input to support regulatory submissions and clinical development activities
• Ensure all activities comply with applicable regulatory and industry standards (e.g., GxP)
• Support tracking of project-level budgets and Medical Affairs activities, as applicable

What This Job Offers

• Career Level: Director
• Education Level: Ph.D. or professional degree