Director, IT Operations

Axsome Therapeutics•New York, NY

13h•$195,000 - $225,000•Hybrid

About The Position

Axsome Therapeutics is seeking a Director, IT Operations who will be responsible for leading and supporting a wide scope of IT operations and business technology programs that underpin Axsome’s business objectives. This position will lead a service desk that provides support for hardware, software, infrastructure, communications and information security related activities throughout the organization, while broadly supporting the IT Team’s operational goals and objectives. This person will also be responsible for maintaining high-priority incidents or requests during non-standard hours, including active weekend and evening and, perform additional responsibilities as assigned by IT leadership. This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.

Requirements

Bachelor's degree in Information Technology, Computer Science, Business, or a related field; equivalent experience may be considered.
10+ years of progressive IT experience in service desk, desktop support, end user computing, or IT operations teams.
At least 5 years of direct leadership experience overseeing helpdesk or service desk operations, including staff supervision, workload management, and performance accountability
Proven expertise in administering ITSM platforms, support workflows, service catalogs, and operational reporting.
Comprehensive knowledge of ITIL practices, incident management, service request management, change coordination, and continual service improvement.
Demonstrated ability to manage vendors, managed service providers, service level expectations, and operational performance reviews.
Excellent communication, leadership, stakeholder management, and customer service skills.
Ability to work on site at least three days per week. We are unable to consider candidates who are looking for fully remote roles.

Nice To Haves

Experience in a biotechnology, pharmaceutical, life sciences, or other regulated environment.
Experience with ServiceNow, Freshservice, Jira Service Management, Microsoft 365, endpoint management, collaboration platforms, and automation tools.
ITIL 4 Foundation/Managing Professional and advanced Microsoft 365/Azure Administrator certifications preferred
Proven ability to scale support operations, improve customer satisfaction, and implement measurable service delivery improvements.
Experience troubleshooting computer and A/V hardware and software, supporting all-level ticket resolution, utilizing helpdesk tools such as JIRA and ServiceNow
Cloud platform administration experience – Microsoft Azure required, and additionally, Amazon Web Services and other cloud-based technologies administration experience beneficial
Experience with deploying and troubleshooting Windows, iOS, and Android devices
Extensive knowledge of administration of the Microsoft stack (M365, Azure, Entra, Intune, Defender)
Experience with Apple Business Manager administration for iOS devices

Responsibilities

Provide strategic leadership and direction for the IT Service Desk, Desktop Support, and End User Support teams, including staffing, workforce planning, performance management, and professional development.
Establish and enforce service delivery standards, operational procedures, and support policies, and build a high-performing support organization focused on exceptional customer service.
Serve as a hands‑on leader when required, providing direct support during complex issues, high‑priority incidents, or resource‑constrained situations.
Oversee the full lifecycle of incidents, service requests, problems, and escalations, including escalation frameworks and major incident management procedures.
Ensure SLAs and KPIs are consistently achieved or exceeded, driving continuous service quality improvements through trend analysis, root cause investigations, and corrective actions.
Engage directly in operational troubleshooting and incident response when needed to maintain service continuity and support team effectiveness.
Own and optimize ITSM platforms including ServiceNow, Freshservice, Jira Service Management, or similar technologies, including workflows, service catalogs, knowledge management, reporting dashboards, and automation initiatives.
Lead ITIL-based service management processes and ensure consistent documentation and governance of support operations across the organization.
Serve as the business-facing owner of the employee IT support experience, monitoring and improving customer satisfaction, service responsiveness, communication quality, and overall support effectiveness.
Develop self-service, knowledge management, and automation strategies that improve employee productivity and reduce repetitive support demand.
Collaborate with business leaders to understand evolving support needs and continuously improve service delivery.
Define, track, and report on operational KPIs including customer satisfaction, service level achievement, mean time to resolution, first contact resolution, ticket volume trends, and support cost effectiveness.
Deliver regular service reviews and operational reporting to IT leadership and business stakeholders, using data and root cause analysis to identify opportunities for automation and process optimization.
Manage relationships with outsourced help desk providers, support vendors, and technology partners, establishing service expectations, governance routines, and performance measures that hold vendors accountable.
Review contracts, statements of work, and support agreements to ensure services align with business requirements and budget expectations.
Oversee endpoint support for laptops, mobile devices, printers, conferencing technologies, and workplace collaboration platforms.
Manage device procurement, deployment, refresh, inventory, and retirement processes, ensuring employees receive timely and effective support for productivity, collaboration, and enterprise applications.
Partner with Information Security and Infrastructure teams to support secure operations and ensure support processes comply with company security policies, audit requirements, and regulatory standards.
Oversee onboarding, offboarding, access management coordination, and endpoint compliance activities.
Participate directly in sensitive or high‑impact support activities to ensure adherence to security and compliance requirements.