Director, Human Resources

RTW Investments•New York, NY

9d•$200,000 - $250,000

About The Position

RTW Investments, LP (“RTW”) is a global, full life-cycle investment and innovation firm dedicated to solving the most challenging, unmet patient needs. We are focused on company building and identifying transformational and disruptive innovations across the biopharmaceutical and medical technologies sectors. Our investment philosophy combines a deep understanding of disease, biology, medicine, and technology with a comprehensive view of commercial opportunities and challenges. Our talented team brings hands-on expertise in targeted areas of innovation, dedicated to the diligent exploration and support of emerging breakthroughs in both industry and academia. Our mission is simple: we power breakthrough therapies that transform the lives of millions. RTW Investments – Recent Press Overview RTW Investments is seeking a highly effective Director of Human Resources to serve as the senior executor and integrator for HR across a hedge fund and its portfolio of newly formed companies. This role is the right hand to the Head of HR and is accountable for building, running, and continuously improving the HR operating system - spanning people operations and recruiting - across multiple entities. In keeping with the firm’s ethos, this is a hands-on role. The Director of HR owns core HR operations, runs the recruiting engine, and personally leads recruiting for priority roles where speed, judgment, or complexity matter. The ideal candidate is a low-ego, systems-driven operator who thrives in complex environments, brings structure to ambiguity, and ensures consistent, high-quality execution. This role is a unique opportunity to become an important part of the Firm Services at RTW.

Requirements

8–12 years of progressive HR experience, ideally in hedge funds, private investment firms, or high-growth, multi-entity environments
Exceptionally strong operator with a track record of building and running scalable HR systems
Comfortable balancing hands-on execution with senior-level partnership
Highly systems-oriented, detail-driven, and organized
Low ego, high ownership; thrives as a trusted second-in-command
Strong judgment and discretion in high-performance, confidential environments
Effective coach and mentor who brings structure and calm to fast-moving teams

Responsibilities

Own and optimize core people operations across the hedge fund and its portfolio companies
Build, standardize, and continuously improve HR processes, including onboarding, performance cycles, compliance, and onboarding and offboarding
Own HR systems and data integrity; ensure accuracy, scalability, and operational rigor
Translate evolving firm needs into durable HR infrastructure that can support multiple entities at different stages
Partner closely with the Head of HR to translate people strategy and organizational design into executable plans
Act as the integrator across HR initiatives, ensuring priorities are clear, work is coordinated, and execution stays on track
Establish operating cadence, dashboards, timelines, and check-ins to provide visibility into headcount, hiring, and HR operations
Surface risks, gaps, and execution issues early; drive resolution
Coach and develop HR team members; provide structure, clarity, and accountability
Raise the bar on execution quality, follow-through, and operating rigor
Design, formalize, and operate a consistent recruiting framework across the fund and newcos
Personally recruit for priority, complex, or high-impact roles, in close partnership with the Head of HR and business leaders
Support leaders with practical guidance on role scoping, interview process, and decision-making
Ensure recruiting execution is fast, disciplined, and aligned with firm standards to support high-quality hiring