Director, HR Business Partner

Madrigal Pharmaceuticals•Waltham, MA

2d•Hybrid

About The Position

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH. Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c). Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way. This HRBP (Director level) is focused on driving critical initiatives such as workforce planning, employee engagement, performance management, and leadership coaching to support Madrigal’s strategic objectives. The position plays a pivotal role in building a high-performance culture by aligning HR programs with the company’s core values—Focus on Patients, Owner Mindset, Innovation, and Collaboration. Key responsibilities include building strong, collaborative relationships with leaders, driving impactful HR initiatives, addressing complex employee relations issues, and enhancing organizational culture and employee engagement to deliver measurable results. Reporting to the Executive Director, HR Business Partnering, this HRBP will support assigned business groups in the Commercial organization as well as other groups as assigned. This role will develop and implement HR strategies that align with the organization’s business objectives and support a high-performance culture.

Requirements

Bachelor’s degree in human resources management (or related field) is required.
10+ years of progressive HR Business Partner experience, with expertise in organizational effectiveness, change management, learning and development, and talent management.
At least 2 years supporting field commercial teams in pharma or biotechnology companies.
At least 3 years of experience supporting or building HR functions within biotech or pharmaceutical organizations and a demonstrated understanding of HR operating models in small to mid-size environments.
Highly organized with exceptional attention to detail, ensuring clarity, accuracy, and precision in work.
Analytical mindset with the ability to interpret data, identify trends, and translate insights into actionable recommendations.
Proficiency in Workday and Microsoft Office Suite (Word, Excel, PowerPoint, Outlook).
Demonstrated consultative style with experience supporting employees and management at all levels.
Excellent communication skills, both verbal and written, with the ability to convey complex ideas clearly and concisely.

Nice To Haves

Graduate degree highly preferred

Responsibilities

Establish trusted, collaborative, and responsive relationships with leaders across the organization, understanding their strategies, priorities, and goals to shape impactful HR programs and priorities that align with Madrigal’s core values.
Lead key HR initiatives, including workforce planning, talent acquisition, employee relations, employee engagement and retention, learning & development, and succession planning, with measurable outcomes in mind.
Coach and develop managers to strengthen their management and leadership skills, fostering high-performing and collaborative teams.
Implement and manage performance management programs that align with Madrigal’s high-performance culture, driving accountability and growth.
Coach to managers and partner with Employee Relations team on ER issues in alignment with Company culture and policies.
Collaborate across HR functions to implement tailored HR programs that address dynamic organizational needs and priorities.
Contribute to HR projects and initiatives on an as-needed basis to drive organizational and operational success.
Establish trusted, collaborative, responsive, and influential relationships with leaders across the organization, understanding their strategies, priorities, and goals.
Utilize this business knowledge to shape HR programs and priorities.