Director, Global Clinical Physician - Early HOCT

Bristol Myers Squibb • Cambridge Crossing, VA

3d • $308,700 - $374,075

About The Position

The Director, Global Clinical Physician serves as a primary source of medical accountability and oversight for multiple clinical trials, manages Phase I/II studies, provides medical and scientific expertise to cross-functional colleagues, and maintains matrix management responsibilities across internal and external networks.

The role independently medically monitors clinical trials from Phase 1 through proof of concept, articulates clinical development strategy, analyzes and interprets trial data, and contributes as a principal functional author for regulatory submissions, study reports, and publications. It provides oversight across the early-development clinical lifecycle, manages medical site interactions, evaluates serious adverse events with Worldwide Patient Safety, contributes to safety narratives, and supports high-performing study delivery teams. The physician also contributes medical and safety expertise to protocol development and fulfills GCP and compliance obligations.

Working with Early Clinical Development leadership and cross-functional partners, the role designs clinical studies and research plans that support asset strategy, including first-in-human, proof-of-concept, registrational, biomarker qualification, and clinical pharmacology studies. It helps define dose and schedule, indications, and patient selection; leads benefit-risk analysis; and supports study delivery, including site activation, enrollment, and adjudication of protocol deviations. The position requires in-depth disease-area knowledge and ongoing engagement with scientific literature and conferences.

The role contributes to health authority interactions and advisory boards, serves as the primary clinical representative in regulatory interactions for early-development projects, and drafts clinical content for study reports and regulatory documents. It also participates in establishing external alliances, supports business development due diligence and partner alliance management, and represents the field through contributions such as publications, patents, or conference participation. The position reports to the Executive Director, Early Clinical Development, Solid Tumors.

Requirements

• Advanced degree in a relevant field: MD, MD/PhD, or ex-U.S. equivalent.
• Clinical expertise in a therapeutic area at attending level or international equivalent.
• At least 5 years of relevant experience in discovery, translational, and/or clinical research in an academic or industry setting, including education where applicable.
• Ability to communicate and present information clearly in scientific and clinical settings.
• Expertise in the scientific method for hypothesis testing, including statistical design, analysis, and interpretation.
• Knowledge of the drug development process.
• Knowledge of the components needed to execute an effective clinical plan and protocols.
• Strong leadership skills and proven ability to lead and work effectively in a team environment.

Nice To Haves

• Subspecialty fellowship training in an applicable therapeutic area.

Responsibilities

• Serve as an independent medical monitor for clinical trials from Phase 1 through proof of concept.
• Provide medical oversight and accountability for multiple trials across the early-development clinical lifecycle.
• Articulate clinical development strategy and analyze, interpret, and act on clinical trial data.
• Serve as principal functional author for regulatory submissions, study reports, and publications.
• Manage site interactions with Clinical Scientists, including medical questions, education, and safety management guidelines.
• Assess key safety-related serious adverse events with Worldwide Patient Safety and oversee contributions to safety narratives.
• Contribute as a key member of Study Delivery Teams and, as applicable, Development Teams.
• Provide medical strategic input into protocol development, including inclusion/exclusion criteria and safety-related considerations.
• Fulfill GCP and compliance obligations and maintain required training.
• Define and establish relationships with key global Phase I centers.
• Design clinical studies and research plans in support of asset strategy, including first-in-human, proof-of-concept, registrational, biomarker qualification, and clinical pharmacology studies.
• Work with Clinical Scientists, Translational and Discovery Scientists, and Development Teams to define dose and schedule, indications, and patient selection.
• Lead benefit-risk analysis for clinical development protocols in a matrix team environment.
• Support study execution with Clinical Scientists, including site activation, enrollment monitoring, and adjudication of protocol violations and deviations.
• Maintain disease-area expertise and keep current through scientific conferences and literature review.
• Contribute to health authority interactions and advisory board meetings, and serve as the primary clinical representative in regulatory interactions for early-development projects.
• Draft clinical content for clinical study reports, regulatory reports, briefing books, and submission documents.
• Participate in establishing alliances with academic centers, cooperative groups, vendors, and government agencies.
• Represent the department in business development due diligence and partner alliance management with oversight.
• Contribute to the field through activities such as publications, patents, or keynote participation at conferences.

Benefits

• Comprehensive benefit plans, including wellbeing support, retirement and financial protection benefits, and medical, dental, vision, life, and disability insurance offerings.
• Flexible Time Off for eligible U.S.-based exempt employees, subject to manager approval.
• 11 paid company holidays each year for eligible U.S.-based exempt employees.
• For specified employee groups, 160 hours of paid vacation annually for new hires, 11 paid company holidays, and 3 optional holidays.
• Depending on eligibility, paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs.
• Eligible employees may receive an annual Global Shutdown between Christmas Day and New Year's Day.
• Potential eligibility for discretionary incentive cash and stock opportunities.

What This Job Offers

• Job Type: Full-time
• Career Level: Director
• Education Level: Ph.D. or professional degree