Director, Degrader Chemistry

BioNTechCambridge, MA
$168,100 - $268,700Onsite

About The Position

The ideal candidate will work in a highly collaborative and cross-functional team to develop antibody drug conjugates (ADCs). The position requires close collaborations with various functional teams, outside partners, CROs, and CDMOs.

Requirements

  • Ph.D. or M.S. in organic chemistry or a related discipline with 8 plus years of industry experience in drug discovery and development
  • Strong experience in protein degraders and molecular glues
  • Proven track record of creative thinking and consistent delivery as demonstrated by publication/presentation records
  • Highly organized with a proactive mentality
  • Thrive in a team center and collaborative environment
  • Excellent interpersonal, networking, and communication skills

Nice To Haves

  • Experience in ADC payload, linker, and conjugation chemistry
  • Experience in ADC manufacturing process development.

Responsibilities

  • Participate in ADC research and development programs by providing chemistry know-how and expertise in protein degraders, molecular glues, payloads, and linkers.
  • Design and synthesize protein degraders and molecular glues
  • Coordinate and collaborate with CMC team supporting process development and GMP manufacturing
  • Prepare preclinical documents for IND filing
  • Work cross-functionally within the R&D organization
  • Collaborate with outside partners, CROs, and CDMOs

Benefits

  • Medical, Dental and Vision Insurance
  • Life, AD&D, Critical Illness Insurance
  • Pre-tax HSA & FSA, DCRA Spending Accounts
  • Employee Assistance & Concierge Program (EAP) available 24/7
  • Parental and Childbirth Leave & Family Planning Assistance
  • Sitterstream: Virtual Tutoring & Childcare Membership
  • Paid Time Off: Vacation, Sick, Bereavement, Holidays (including Floating) & Year-End U.S. Shutdown.
  • 401(K) Plan with Company Match
  • Tuition Reimbursement & Student Loan Assistance Programs
  • Wellbeing Incentive Platforms & Incentives
  • Professional Development Programs
  • Commuting Allowance and subsidized parking
  • Discounted Home, Auto & Pet Insurance
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