Director, Commercial Strategy and Business Development Assessment

Sobi • Waltham, MA

1d • Hybrid

About The Position

The Director, Commercial Strategy & Business Development Assessment is responsible for supporting U.S. commercial assessments, commercialization planning, strategic evaluations, policy assessments, and integration planning activities for external business development opportunities and internal portfolio expansion initiatives. This role serves as a key commercial assessment partner for evaluating acquisition, licensing, partnership, and portfolio investment opportunities by assessing market attractiveness, patient opportunity, pricing potential, reimbursement feasibility, commercialization requirements, operating model design, competitive dynamics, and long-term value creation potential. This role bridges commercial strategy, commercialization planning, market access, pricing, business development assessment, portfolio evaluation, policy assessment, and integration planning to support informed investment decisions and long-term portfolio growth. In addition, this role supports Market Access policy initiatives and post-acquisition integration planning by partnering with Market Access leadership, Business Development, and the central integration team to ensure successful evaluation, planning, and execution of new opportunities.

Requirements

• Bachelor’s degree required.
• 8-10+ years of progressive pharmaceutical, biotechnology, healthcare consulting, commercial strategy, commercial development, market access, portfolio strategy or business development experience.
• Experience conducting commercial due diligence, portfolio assessments, strategic business analyses or asset evaluations.
• Specialty pharmaceutical or biotechnology experience required.
• Rare disease experience strongly preferred.
• Experience evaluating assets across multiple therapeutic areas.
• Experience developing commercial assessments supporting acquisition, licensing, portfolio investment, launch planning or commercialization decisions.
• Experience assessing commercial opportunities through pricing, reimbursement, market access, commercialization requirements, operating model design and launch readiness.
• Exceptional commercial acumen and strategic thinking capabilities.
• Strong understanding of pharmaceutical pricing, reimbursement, market access, commercialization and portfolio evaluation principles.
• Strong analytical and quantitative skills.
• Executive communication and presentation skills.
• Ability to influence without direct authority.

Nice To Haves

• MBA, MPH, PharmD, PhD or equivalent advanced degree preferred.
• Experience developing commercialization plans, operating models, sales force assumptions, patient support strategies and launch readiness assessments preferred.
• Experience evaluating healthcare policy developments and assessing implications for pharmaceutical pricing, reimbursement, market access, and commercial strategy preferred.
• Experience supporting commercial integration, launch readiness, acquisition integration, or portfolio transition activities preferred.
• Experience working with cross-functional integration teams and organizational change initiatives preferred.

Responsibilities

• Lead U.S. commercial assessments for acquisition, licensing, partnership and strategic business development opportunities.
• Evaluate strategic fit, unmet need, treatment paradigms, competitive intensity, market attractiveness and long-term commercial potential.
• Support internal portfolio strategy initiatives including new indications, lifecycle management opportunities, reformulations and line extensions.
• Develop recommendations regarding commercial viability, launch feasibility, investment requirements, organizational implications and key risks.
• Assess alignment with corporate strategy and long-term growth objectives.
• Lead commercial due diligence activities.
• Assess epidemiology, diagnosed populations, treated populations, addressable patient populations, treatment algorithms and site-of-care dynamics.
• Develop market sizing methodologies and opportunity assessments.
• Conduct primary and secondary research to validate assumptions.
• Partner with Business Analytics to validate epidemiology, patient opportunity and forecast inputs.
• Evaluate competitive landscapes, pipeline threats and future market evolution.
• Participate actively in diligence meetings with target companies and consultants.
• Develop pricing recommendations and commercial pricing frameworks.
• Evaluate pricing potential relative to clinical differentiation and payer expectations.
• Develop gross-to-net assumptions and reimbursement frameworks.
• Assess Medicare, Medicaid, Commercial, Specialty Pharmacy and Buy-and-Bill reimbursement implications.
• Evaluate payer management expectations, utilization management risks and access barriers.
• Assess coding, payment, contracting, distribution and channel considerations.
• Support assessment of evolving healthcare policy initiatives and their potential impact on commercial opportunity, pricing strategy, reimbursement, and long-term asset value.
• Partner with Market Access leadership to evaluate policy developments related to GLOBE, GUARD, GENEROUS, MFN initiatives, and other pricing and reimbursement reform efforts.
• Support NPC-related activities and monitor emerging policy developments and potential business implications.
• Develop analyses evaluating policy-related risks and opportunities associated with acquisition, licensing, and portfolio opportunities.
• Support scenario planning exercises assessing policy impacts on pricing, reimbursement, access, contracting, and commercialization assumptions.
• Collaborate with Market Access subject matter experts to incorporate policy considerations into asset evaluations and strategic recommendations.
• Develop commercialization strategies and launch planning recommendations.
• Assess launch feasibility and organizational capabilities required for commercialization.
• Develop recommendations regarding sales force size, deployment models, targeting strategies and customer engagement approaches.
• Assess patient support services, HUB operations, field reimbursement, nurse educator requirements, specialty pharmacy support and distribution strategies.
• Partner with Finance to develop commercialization investment assumptions and operating expense estimates.
• Develop build-versus-buy recommendations and organizational capability assessments.
• Support Market Access integration planning activities for acquired, licensed, or partnered assets.
• Serve as the primary Market Access liaison to the central integration management team for assigned opportunities.
• Develop recommendations regarding Market Access integration requirements, including pricing, reimbursement, patient support, contracting, distribution, field reimbursement, and access strategy considerations.
• Partner with cross-functional stakeholders to identify integration risks, capability gaps, resource requirements, and implementation timelines.
• Support development of integration workplans and readiness assessments.
• Coordinate Market Access deliverables associated with integration activities and commercialization planning.
• Monitor progress against integration milestones and support issue identification and resolution.
• Develop recommendations regarding future-state operating models and organizational requirements for integrated assets.
• Develop commercial assumptions related to pricing, reimbursement, access, uptake, competitive response and lifecycle opportunities.
• Support scenario planning and sensitivity analyses.
• Partner with Finance and Business Development to refine revenue assumptions and investment scenarios.
• Assess clinical differentiation, value proposition strength and competitive positioning.
• Evaluate evidence requirements necessary to support reimbursement and adoption.
• Identify evidence gaps impacting commercial success.
• Partner across Business Development, Commercial, Market Access, Medical Affairs, Business Analytics, Finance, Regulatory and Legal.
• Support leadership decision-making through objective, data-driven recommendations.

Benefits

• Competitive compensation for your work
• Generous time off policy
• Summer Fridays
• Opportunity to broaden your horizons by attending popular conferences
• Emphasis on work/life balance
• Collaborative and team-oriented environment
• Making a positive impact to help ultra-rare disease patients who are in need of life saving treatments
• A competitive 401(k) match to support your financial future.
• Tuition and wellness reimbursements to invest in your personal and professional growth.
• A comprehensive medical, dental, and vision package to prioritize your health and well-being.
• Additional recognition awards to celebrate your achievements.

What This Job Offers

• Job Type: Full-time
• Career Level: Director