Director, Clinical Supply Chain

Frontier Medicines•Boston, MA

6d•$215,000 - $275,000

About The Position

Frontier is looking for a Director/Sr. Director, Clinical Supply Chain to build and lead clinical trial supply strategy across our growing clinical portfolio. This is a hands-on, high-visibility role responsible for ensuring investigational product is forecasted, packaged, labeled, and delivered to clinical sites on time and in compliance with GMP/GCP requirements, keeping pace with an evolving trial portfolio. Reporting to the Head of Technical Operations and CMC, this role will partner closely with CMC, Clinical Operations, Quality, and Regulatory Affairs to keep supply ahead of trial demand as Frontier's pipeline advances.

Requirements

Bachelor's degree in a scientific, supply chain, or related field; advanced degree a plus.
8+ years (Director) or 10+ years (Sr. Director) of clinical supply chain experience in biotech or pharma, including oncology trial experience.
Direct experience with IRT/IWRS systems, clinical packaging and labeling, and global clinical distribution.
Working knowledge of GMP/GCP requirements as they apply to clinical supply.
Experience managing CMO/CPO and distribution/depot vendor relationships.
Strong cross-functional collaboration skills, particularly with CMC/Technical Operations, Clinical Operations, Quality, and Regulatory Affairs.
Comfortable in a fast-paced, dynamic environment; a proactive, roll-up-your-sleeves mindset appropriate for a lean, growing organization.
Legally authorized to work in the United States.

Nice To Haves

Oncology trial experience

Responsibilities

Own end-to-end clinical supply chain strategy for active and upcoming trials
Develop and maintain clinical drug supply forecasts and demand plans, translating protocol design, enrollment projections, and dosing regimens into packaging, labeling, and distribution plans.
Select and manage clinical packaging, labeling, and distribution vendors, including oversight and performance management of CMOs/CPOs and specialty distribution/depot partners.
Own Interactive Response Technology (IRT/IWRS) requirements, build, and testing in partnership with Clinical Operations, and serve as the clinical supply lead on IRT vendor management.
Manage comparator and ancillary supply sourcing, including global sourcing strategies where applicable.
Oversee cold chain and temperature-controlled logistics, expiry/re-test date management, and label reconciliation across depots and sites.
Partner with CMC/Technical Operations to align clinical supply timelines with drug substance and drug product manufacturing schedules.
Ensure compliance with GMP, GCP, and applicable import/export regulations across all clinical supply activities, including serialization and country-specific labeling requirements.
Support regulatory submissions with clinical supply chain content (e.g., IMPD/IND sections, label text) in partnership with Regulatory Affairs and Quality.
Manage clinical supply budget, purchase orders, and vendor invoicing in partnership with Finance.
Build scalable clinical supply chain processes and systems as Frontier's clinical portfolio and trial complexity grow.