Director, Clinical Data Management

Bristol Myers Squibb • San Diego, CA

1d • $227,418 - $275,577 • Onsite

About The Position

At RayzeBio, every day is an opportunity to ignite meaningful change. As a wholly-owned subsidiary of Bristol Myers Squibb, RayzeBio blends the nimble, pioneering spirit of an emergent biotech with the global expertise and resources of a leading innovator in oncology. Our mission is to develop transformative radiopharmaceutical therapies that offer new hope for patients living with cancer. Here, you’ll join a multidisciplinary team where your ideas are valued, your expertise is amplified, and collaboration is at the heart of everything we do. From day one, expect to make an immediate impact—on our science, on our teams, and most importantly, on patients. Learn more about RayzeBio: https://careers.bms.com/rayzebio/ Director, Head of Clinical Data Management Summary: RayzeBio, a Bristol Myers Squibb company, is a dynamic biotechnology company headquartered in San Diego, CA. The company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. RayzeBio is developing innovative drugs against targets of solid tumors. Led by a successful and experienced entrepreneurial team, RayzeBio aims to be the global leader in radiopharmaceuticals The Director, Clinical Data Management, will lead the Data Management function at RayzeBio, providing both strategic leadership and hands-on operational oversight across the clinical portfolio. Reporting to the Head of Biometrics, this role is responsible for ensuring the accuracy, integrity, consistency, and regulatory readiness of clinical trial data from study start-up through NDA/BLA submission. The ideal candidate combines strong technical, operational, and leadership expertise with the ability to build scalable processes, oversee CROs and vendors, drive cross-functional collaboration, and proactively resolve complex data challenges in a fast-paced development environment.

Requirements

• Strong knowledge and experience of EDC systems (Medidata RAVE or Veeva).
• Solid knowledge of GCP, CDISC/CDASH data structures, ICH guidelines and FDA regulations.
• Excellent verbal and written communication skills.
• Strong analytical and problem-solving abilities.
• Bachelor’s or Master’s degree in Life Sciences, Computer Science, Mathematics, Health Sciences, or a related field required.
• Minimum of 10 years data management experience in pharmaceutical/biotech/CRO industry.
• Demonstrated experience in team leadership and management.
• Ability to guide, mentor, and develop team members.
• In-depth experience in the Oncology therapeutic area is required.
• Proven ability to manage CRO relationships and oversee data management deliverables.
• Experience utilizing AI-enabled tools to improve productivity and work efficiency.

Nice To Haves

• Experience with Veeva EDC system
• Radiopharmaceutical experience preferred.

Responsibilities

• Lead the Clinical Data Management function at RayzeBio, providing strategic and operational oversight across the clinical portfolio.
• Serve as the Data Management lead for a high-priority clinical development program, maintaining hands-on involvement in study execution, data review, issue resolution, and risk management.
• Provide leadership for NDA/BLA submission activities, including submission readiness, data standards compliance, and regulatory inspection preparedness.
• Partner cross-functionally with Clinical Operations, Biostatistics, Statistical Programming, Medical Monitoring, Safety, and Regulatory Affairs to support study execution and data quality objectives.
• Oversee CROs and vendors, ensuring quality, compliance, accountability, and adherence to timelines and deliverables.
• Lead ongoing cross-functional data review activities and oversee development of key data management documentation, including Data Management Plans, edit checks, validation specifications, reconciliation plans, and data transfer agreements.
• Develop and implement scalable data management processes, standards, governance, and SOPs to support operational excellence and organizational growth.
• Manage competing priorities across multiple studies while proactively identifying operational risks and mitigation strategies.
• Build, develop, and expand the Clinical Data Management team, and foster a collaborative and high-performing team environment.
• Willing to travel approximately 10% of the time.
• Evening and weekend work will be involved.

Benefits

• Medical, pharmacy, dental, and vision care.
• Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
• Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
• Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
• Based on eligibility, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
• All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

What This Job Offers

• Job Type: Full-time
• Career Level: Director