Director, AI and Agentic Engineering

ExelixisAlameda, CA
$215,000 - $306,000Onsite

About The Position

The Director, Engineering AI and Agentic leads the strategy, architecture, delivery, and operations of enterprise AI platforms and AI-enabled business solutions. This role combines deep AI engineering leadership with strong product management capabilities to translate business needs into scalable, secure, measurable, and user-centered AI products. The Director, Engineering AI And Agentic is accountable for building reusable AI platform capabilities, delivering production-grade agentic and generative AI solutions, advancing AI-native engineering practices, and partnering across IT, security, data, legal, compliance, and business stakeholders to responsibly scale AI adoption across Exelixis.

Requirements

  • Bachelor’s degree in a related discipline and 13 years of related experience; or Master’s degree in a related discipline and 11 years of related experience; or Equivalent combination of education and experience.
  • 5+ years in AI Engineering or Cloud platform Engineering
  • Leadership experience, overseeing cross-functional teams
  • Experience in full lifecycle system development (design, implementation, validation and support) of cloud based solutions and platforms
  • Advanced understanding of AI engineering, generative AI, agentic AI patterns, AI platform architecture, software engineering, cloud-native design, enterprise integration, and production operations.
  • Strong ability to define platform strategy, product roadmaps, business cases, success metrics, delivery plans, and adoption approaches for enterprise AI capabilities.
  • Hands-on technical credibility with modern AI solution patterns, including LLMs, prompt/context engineering, tool use, multi-step workflows, agent orchestration, retrieval-augmented generation, vector search, evaluation, monitoring, and guardrails.
  • Experience with cloud AI and data platforms such as AWS, Amazon Bedrock, Databricks Mosaic AI, or equivalent technologies; familiarity with APIs, event-driven architectures, data pipelines, identity, secrets management, and enterprise security patterns.
  • Demonstrated ability to lead AI-native engineering practices using coding agents, AI-assisted development tools, specification-driven development, automated testing, CI/CD, DevSecOps, observability, and continuous improvement.
  • Strong understanding of responsible AI, data governance, privacy, cybersecurity, model risk, auditability, human-in-the-loop controls, regulatory expectations, and enterprise policy compliance.
  • Excellent leadership skills with the ability to recruit, mentor, coach, and develop diverse technical teams while setting clear standards for quality, accountability, innovation, and delivery excellence.
  • Strong communication, executive presence, facilitation, stakeholder management, and influencing skills; able to translate complex AI concepts into business implications, risks, tradeoffs, and decisions.
  • Ability to work effectively in ambiguous and fast-changing environments, make informed tradeoffs, resolve conflicts, and align cross-functional teams around outcomes.
  • Advanced planning, portfolio management, vendor management, financial management, and execution skills with the ability to manage multiple initiatives across a matrixed organization.

Nice To Haves

  • Knowledge of life sciences, biotechnology, clinical, regulatory, GxP, SOX, 21 CFR Part 11, or validated system environments is preferred.

Responsibilities

  • Define and execute the AI engineering strategy, roadmap, and operating model for enterprise AI platforms, reusable services, and AI-enabled business solutions.
  • Lead the design and delivery of scalable AI platform capabilities, including model access patterns, agent orchestration, retrieval-augmented generation, evaluation frameworks, prompt and artifact management, observability, governance controls, and reusable integration patterns.
  • Oversee end-to-end development of production-grade generative AI, agentic AI, and automation solutions that improve productivity, decision support, operational efficiency, and business outcomes across functions.
  • Apply strong product management practices, including opportunity assessment, stakeholder discovery, prioritization, roadmap planning, user experience definition, value measurement, adoption planning, and lifecycle management.
  • Partner with business leaders, product managers, architects, data teams, cybersecurity, privacy, legal, compliance, and enterprise application teams to translate strategic business needs into secure, governed, and scalable AI solutions.
  • Establish AI-native engineering standards and practices, including specification-driven development, agent-assisted software delivery, automated testing, code quality, reusable patterns, DevSecOps, CI/CD, release management, and operational support models.
  • Ensure AI solutions are designed for reliability, security, scalability, auditability, explainability, human oversight, measurable autonomy, and responsible AI use consistent with company policies and regulatory expectations.
  • Manage platform, and technology decisions across AI providers, cloud services, data platforms, development tools, and open-source components; assess build-versus-buy options and total cost of ownership.
  • Create and monitor success metrics for AI platforms and solutions, including adoption, productivity impact, quality, latency, cost, risk reduction, reuse, user satisfaction, and business value realization.
  • Lead architecture reviews, prompt and solution reviews, security reviews, model and agent evaluations, release-readiness assessments, and post-production performance monitoring.
  • Develop talent, delivery practices, technical documentation, playbooks, reference architectures, and enablement materials that help teams adopt AI-native engineering safely and effectively.
  • Performs other duties as assigned
  • Complies with all policies and standards

Benefits

  • 401k plan with generous company contributions
  • group medical, dental and vision coverage
  • life and disability insurance
  • flexible spending accounts
  • discretionary annual bonus program
  • opportunity to purchase company stock
  • long-term incentives
  • 15 accrued vacation days in their first year
  • 17 paid holidays including a company-wide winter shutdown in December
  • up to 10 sick days throughout the calendar year
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