PGS-Digital Portfolio Governance & Realization Lead

Pfizer • New York City, NY

8d • Hybrid

About The Position

The PGS Digital Portfolio Governance Lead reports to the VP, PGS Data, Analytics & AI Transformation and serves as a member of the leadership team. The role operates in a 50/50 partnership with Digital leadership, with critical input from functional leaders across PGS, and is accountable for developing, governing, and realizing the PGS-Digital strategy in alignment with the PGS LT-endorsed strategy. This leader establishes the portfolio governance, investment discipline, and value realization framework that ensures approved PGS-Digital initiatives are prioritized, funded, tracked, delivered, adopted, and sustained. The role owns the mechanisms that make progress, spend, risks, and business case outcomes visible, enabling rapid identification of off-track work and clear accountability for remediation, redesign, or retirement where needed. The scope includes Engagement & Adoption leadership and Project Management Office capacity for select major initiatives, both of which are critical to converting strategy and investment into measurable business impact. Through disciplined governance, rigorous execution, and sustained adoption, the role helps Pfizer realize the full value of PGS-Digital, Data, Analytics, and AI transformation investments.

Requirements

• Bachelor’s degree in Business, Finance, Information Systems, Engineering, Project/Program Management, or related field with 12+ years of relevant experience; OR master’s degree with 10+ years of relevant experience; OR PhD with 7+ years of relevant experience.
• Demonstrated success leading enterprise-scale digital portfolio governance, investment prioritization, value realization, program management, or change management capabilities with senior-management accountability.
• Proven ability to translate enterprise or divisional strategy into aligned initiatives, investment decisions, business cases, governance routines, budgets, and measurable value outcomes.
• Experience leading complex, cross-functional programs or PMO capabilities in highly matrixed, global organizations, including accountability for delivery discipline, risk escalation, remediation, and sustained adoption.
• Demonstrated ability to partner with Digital, Finance, Quality, Regulatory, and business leaders to guide shared decisions across portfolio priorities, lifecycle management, compliance expectations, and issue resolution.
• Strong understanding of digital solution portfolios, including data and analytics platforms, AI/ML solutions, enterprise applications, citizen development tools, and emerging technologies.
• Excellent executive communication, facilitation, judgment, and influencing skills.
• Business-level fluency in English (written and verbal) required for effective global collaboration and executive communication.
• Permanent work authorization in the United States.

Nice To Haves

• Professional certification in Portfolio Management, Program/Project Management, Change Management, Agile, or related discipline.
• Strong AI, digital, financial, and business acumen, with ability to connect portfolio strategy and investment governance to PGS supply chain, manufacturing, and enterprise priorities.
• Execution focus from strategy through realization and sustainment, with a proven change-agent track record driving adoption and measurable outcomes in large, complex organizations.
• Excellent presentation, facilitation, and executive storytelling skills across initiative owners, technical teams, functional partners, and senior leadership.
• Strong Pfizer network across PGS, Digital, Finance, Quality, Regulatory, and other enabling functions.

Responsibilities

• Partner with Digital leadership in a 50/50 operating model to translate PGS strategy, as set by the PGS President and PGS LT, into an aligned PGS-Digital strategy and prioritized set of initiatives.
• Ensure the strategy is traceable to overarching PGS priorities and secured through appropriate PGS LT endorsement before informing investment, governance, and execution decisions.
• Guide strategic investment decisions by directing where the division invests to realize PGS LT strategy through disciplined prioritization across major PGS-Digital initiatives.
• Own the lifecycle of major PGS-Digital investments, including business case development, annual budgeting inputs, portfolio prioritization, trade-off decisions, program governance, total cost of ownership analysis, lifecycle management, risk escalation, and issue remediation.
• Establish and maintain a review framework that makes initiative performance visible across progress, spend, timelines, risks, adoption, and value delivered against approved business cases.
• Maintain a trusted network of functional partners and hold initiative owners accountable for remediation plans, course correction, redesign, or retirement when performance, value, or adoption is off track.
• Lead major, multi-tower program management on behalf of the organization, including PMO support for Trusted Data & Responsible AI and other large, cross-cutting Data, Analytics & AI initiatives.
• Maintain Project Management Office capacity for select major initiatives and targeted supplemental support for other PGS-Digital priorities, reinforcing disciplined delivery and transformation execution.
• Lead the Engagement & Adoption function, providing organization-wide standards, coaching, and selective hands-on execution support to ensure critical PGS-Digital solutions and process changes are embedded and sustained.
• Provide change management, stakeholder engagement, communications, feedback mechanisms, recognition, and collaboration practices that strengthen adoption across the portfolio and the broader PGS Data, Analytics & AI Transformation organization.
• Partner with Quality, Digital, and other policy-owning organizations to ensure in-scope programs adhere to applicable corporate, PGS, and Digital policies, standards, controls, documentation, catalog/inventory registration, and performance monitoring expectations.
• Drive organization-wide awareness of governance, compliance, and documentation expectations so colleagues understand what is and why.
• Represent the organization in relevant Digital, Quality, and PGS governance forums spanning investment decisions, compliance matters, and major cross-tower programs.
• Coordinate with fellow leaders across PGS Data, Analytics & AI Transformation and delegate participation where appropriate while ensuring the organization presents a consistent, unified voice across the enterprise governance landscape.

Benefits

• 401(k) plan with Pfizer Matching Contributions
• Additional Pfizer Retirement Savings Contribution
• Paid vacation, holiday and personal days
• Paid caregiver/parental and medical leave
• Health benefits to include medical, prescription drug, dental and vision coverage

What This Job Offers

• Job Type: Full-time
• Career Level: Senior