Development Associate, Oncology

BillionToOne•Menlo Park, CA
•$76,155 - $87,034•Onsite

About The Position

BillionToOne is seeking a Development Associate to join its Oncology Development and Process Engineering team, supporting clinical patient testing in a high-throughput CLIA laboratory. The role offers experience in molecular assay development, data analysis, experimental design, and automation. It is an on-site position, with the majority of workdays spent in the Menlo Park office. The Development Associate will develop and extend assays for evolving clinical needs, analyze experimental data using computational methods, support validation and regulatory activities, and carry out and document laboratory experiments. The role also contributes to lab organization, communicates technical findings, partners with other departments to transfer and scale assays into clinical operations, and investigates sources of process variation to improve methods.

Requirements

  • Bachelor’s, Master’s, or equivalent degree in Molecular Biology, Biochemistry, Cell Biology, Microbiology, Biophysics, or a related field.
  • At least 12 months of experience using molecular biology techniques, such as PCR, electrophoresis, and DNA purification, in a research or clinical laboratory; experience may be gained during or after a bachelor’s degree.
  • A solid foundation in quantitative data analysis, statistics, and experimental design.
  • Familiarity with R or Python and a strong willingness to expand computational skills.
  • Clear verbal and written communication skills for reporting to cross-functional teams of scientists and non-scientists.
  • Demonstrated experimental troubleshooting and root-cause analysis skills, with close attention to detail.

Nice To Haves

  • Start-up experience.
  • Experience with next-generation sequencing (NGS) and/or cell-free DNA.
  • Experience with liquid handling or other laboratory automation.
  • Knowledge of molecular oncology.
  • Experience composing protocols for standard molecular biology techniques.

Responsibilities

  • Develop and extend existing assays to address evolving clinical needs, working with scientists, engineers, and other technical staff.
  • Apply computational and analytical methods used in current assays and develop new capabilities; create, implement, and use software tools to quantitatively analyze experiments and processes.
  • Support assay validations and risk reduction under regulatory and design-control frameworks, including FDA and MolDx.
  • Present technical findings and project updates in group meetings and internal written reports.
  • Conduct and document laboratory experiments and procedures, and help organize the R&D laboratory.
  • Partner across departments to transfer and scale developed assays and workflows into high-throughput clinical laboratory operations.
  • Apply engineering practices to scale, optimize, and improve molecular biology methods; investigate sources of variation and develop corrective and preventative measures.

Benefits

  • Multiple medical benefit options, with employee premiums fully paid for select plans and dependent coverage up to 80%.
  • 16 weeks of paid Family Bonding Leave at 100% for eligible employees.
  • Supplemental fertility benefits coverage.
  • Retirement savings program with a 4% company match.
  • Paid time off that increases with tenure.
  • Company-provided hardware, laboratory equipment, and facilities.
  • Free daily on-site lunches.
  • Campus amenities and perks, including a shuttle to and from select transit hubs, a gym, and a restaurant.
  • Free on-site EV charging.
  • Equity options and company benefits, including free healthcare options.
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