Cryo-Electron Microscopy Specialist

Axle • Hamilton, MT

4d • $90,000 - $110,000 • Onsite

About The Position

Axle is seeking a skilled Cryo-electron microscopist to join the Research Technologies Branch (RTB), Electron Microscopy Unit (EMU) at Rocky Mountain Laboratories (RML) in Hamilton, Montana. This is a hands-on, collaborative role where you will work closely with scientists to generate high-quality data supporting infectious disease research. The position is ideal for someone who enjoys the technical aspects of electron microscopy and is eager to learn and apply newer approaches such as room-temperature EM, FIB-SEM, and cryo-EM.

Requirements

• Master's degree or higher in a relevant field (Cell Biology, Structural Biology, Biophysics, or similar).
• Solid understanding of EM sample preparation and imaging workflows.
• Experience operating and troubleshooting EM instruments.
• Strong communication skills.
• Ability to work collaboratively.
• Comfortable supporting multiple projects.

Nice To Haves

• Experience with, or strong interest in learning: Room temperature electron microscopy
• Experience with, or strong interest in learning: Correlative Light and Electron Microscopy (CLEM)
• Experience with, or strong interest in learning: Focused Ion Beam-SEM (FIB-SEM)
• Familiarity with image analysis tools.

Responsibilities

• Perform negative staining on purified proteins to evaluate sample quality.
• Prepare biological samples for cryo-EM (plunge freezing) and perform imaging and analysis.
• Operate and help maintain TEM and other ancillary instruments, including troubleshooting when needed.
• Work closely with NIAID investigators to plan experiments, interpret results, and solve technical challenges.
• Help bring new capabilities online, including techniques like CLEM, FIB-SEM, and cryo-EM.
• Keep clear, well-organized records in line with NIH standards for rigor and reproducibility.
• Train and support other lab members or facility users in EM techniques and image processing.
• Contribute to the overall operation of the lab, including equipment upkeep and safety compliance.

Benefits

• 100% Medical, Dental & Vision Coverage for Employees
• Paid Time Off and Paid Holidays
• 401K match up to 5%
• Educational Benefits for Career Growth
• Employee Referral Bonus
• Flexible Spending Accounts: Healthcare (FSA)
• Flexible Spending Accounts: Parking Reimbursement Account (PRK)
• Flexible Spending Accounts: Dependent Care Assistant Program (DCAP)
• Flexible Spending Accounts: Transportation Reimbursement Account (TRN)

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level