Core Research Assistant - Mass Spectrometry

Staff Career•La Jolla, CA

About The Position

The Salk Institute Mass Spectrometry Core facility conducts mass spectrometry-based metabolomics and proteomics analyses using advanced instrumentation to support Salk research. The Core Research Assistant prepares samples, operates and maintains equipment, and processes data for liquid chromatography-mass spectrometry (LC-MS) analysis of small to large molecules. The role also supports facility users and participates in project discussions and weekly Core meetings. Sample preparation may involve hazardous chemicals, including strong solvents, acids, and bases, and biohazardous materials such as human-derived plasma or serum.

Requirements

  • Bachelor’s degree in a relevant field or an equivalent combination of education and experience.
  • Experience in sample preparation and/or LC-MS instrument operation for metabolomics or proteomics.
  • Excellent communication skills and ability to collaborate with diverse research teams.
  • Ability to read, comprehend, and discuss research materials.
  • Strong organizational skills and attention to detail.
  • Organizational and time-management skills to set priorities, meet deadlines, recognize new problems, and manage changing priorities and frequent interruptions.
  • Ability to work independently and as part of a team in a fast-paced research environment.
  • Knowledge of standard laboratory and safety procedures.

Nice To Haves

  • Experience in a core facility or shared resource setting.
  • Experience with LC-MS data processing and statistical analysis of results.
  • Theoretical and practical knowledge of biology related to metabolomics or proteomics results.

Responsibilities

  • Safely prepare samples for LC-MS metabolomics and proteomics analysis, including handling hazardous chemicals and biohazardous materials.
  • Maintain and operate LC-MS equipment, ensuring optimal performance and safety standards.
  • Process LC-MS-acquired data using metabolomics and proteomics software.
  • Participate in individual project discussions and weekly group meetings held by the Core.
  • Assist with troubleshooting technical issues and perform routine equipment maintenance.
  • Maintain accurate records of experiments and instrument usage.
  • Provide support to facility users.
  • Perform other related duties as assigned by management.

Benefits

  • Medical benefits
  • Dental insurance
  • Vision insurance
  • Retirement benefits
  • Paid time off
  • Tuition reimbursement
  • Patient advocacy services
  • Transit and parking program
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