Configuration Lead MES

Sanofi • Toronto, ON

6d • CA$158,200 - CA$208,200 • Onsite

About The Position

Sanofi's manufacturing network is undergoing a fundamental digital transformation — moving from paper-based systems to fully integrated, GxP-compliant MES environments across 30+ global sites. The MES Digital Configuration Lead is the technical backbone of this transformation. Based at Sanofi Pasteur's major Toronto site — one of Sanofi's most strategic manufacturing hubs in the Americas — you will drive the design, build, and lifecycle of Sanofi's global MES solutions (Siemens Opcenter Execution Pharma / Körber PAS-X), ensuring core model consistency, GxP compliance, and strong business alignment across the manufacturing network. Working closely with Product Owners, digital teams, and industrial sites worldwide, this role covers architecture, configuration, integration, and continuous improvement of MES deployments at global scale. This is not a support role — it is a senior strategic leadership position with direct impact on patient safety, regulatory standing, and Sanofi's ability to scale manufacturing digitalization globally.

Requirements

• 5+ years of experience in MES / Industrial IT.
• Experience in a regulated Pharmaceutical / Life Sciences environment (GxP).
• Multi-site, international, and/or matrix organization experience is highly valued.
• Experience gained in pharma, biotech, consulting, or as a vendor/system integrator is equally appreciated.
• Strong expertise in pharmaceutical MES solutions; Siemens Opcenter Execution Pharma experience preferred.
• Candidates with significant experience in other leading MES platforms will also be considered.
• Master Batch Record (MBR), Review by Exception, MES modules, and system integrations.
• Scripting skills: SQL, VB.NET/C#, Python, or MES platform-specific languages.
• GxP, Data Integrity, CSV/CSA, and GAMP5.
• Solution architecture and ERP/LIMS/shopfloor integrations.
• Understanding of automation environments including SCADA, DCS, PLCs, and industrial protocols.
• Engineering degree or Master's degree in Computer Science, Industrial IT, Automation, or equivalent professional experience.
• English mandatory

Nice To Haves

• Knowledge of Körber PAS-X (adaptability and willingness to learn is key).
• Low-code application development using Mendix.
• AI-assisted development tools (GitHub Copilot, Claude, Microsoft Copilot, etc.).
• Cloud architecture and services (Azure preferred).
• French appreciated.

Responsibilities

• Master Data Management
• Master Batch Record (edition, approval, Review by Exception)
• Production Execution
• Weighing & Dispensing
• Equipment & Material Flow Management
• Traceability/Genealogy
• Labelling
• Reporting
• ERP, LIMS, SCADA, Deviation Management, Serialization and OEE integrations
• Translate business needs into standardized, compliant MES designs scalable across multi-GBU and multi-site configurations.
• Drive core model adoption and ensure consistent deployments across industrial sites globally.
• Provide functional and technical leadership throughout the full solution lifecycle.
• Demonstrate deep technical understanding of MES architecture, configuration, and integrations.
• Diagnose and resolve complex technical issues across platforms, interfaces, and automation layers.
• Apply scripting skills (SQL, VB.NET/C#, Python, or platform-specific scripting) for configuration, automation, and troubleshooting.
• Bridge functional design and technical implementation; act as escalation point for critical issues.
• Design and build core solutions aligned with market standards and industrial best practices.
• Conduct end-to-end process analysis including integrations (ERP, LIMS, SCADA, DCS, labelling, mobile).
• Evaluate impact analysis, manage risks, and ensure on-time, cost-effective delivery.
• Ensure compliance with GxP, Data Integrity, 21 CFR Part 11, and Sanofi quality standards.
• Provide expert guidance and functional leadership to MES configuration teams across sites.
• Facilitate knowledge transfer and contribute to Digital skills development across the network.
• Benchmark technology trends and bring innovative inputs to solutions and operating models.
• Collaborate with Enterprise Architects, Cybersecurity, and Technical Architects on solution design.
• Challenge established GxP validation approaches to adapt to next-generation technologies such as Cloud, Agile methodologies, and CSA.

Benefits

• Global Impact — Contribute to MES solutions deployed across more than 30 manufacturing sites.
• Stability & Ownership — A permanent, in-house role with direct influence on Sanofi's global MES landscape.
• Mission-Driven Work — Direct contribution to manufacturing excellence, product quality, and patient safety.
• Career Growth — Opportunities to progress toward Product Management, or Digital Manufacturing leadership positions.
• Learning & Development — Access to Digital Academy and industry certifications.
• Inclusive Culture — A collaborative, international environment.
• high-quality healthcare
• prevention and wellness programs

What This Job Offers

• Job Type: Full-time
• Career Level: Senior