Commercial Affordability Principal Project Manager

GenentechDaly City, CA
$136,100 - $252,700Hybrid

About The Position

The Commercial Affordability Principal Project Manager will serve as a key cross-portfolio subject matter expert driving the end-to-end operational execution of Genentech’s commercial affordability programs (including Co-pay, Bridge/Starter, Coupon other patient free goods programs). This role involves owning day-to-day operations for multiple commercial affordability programs across diverse brand and therapeutic areas, managing external vendor performance, and leading complex, cross-functional operational initiatives. The position requires performing root-cause analysis on systemic operational issues, interpreting program performance data to deliver actionable insights, and ensuring strict program compliance with regulatory guidelines, internal policies, and operational guardrails. The role also acts as a primary subject matter expert and cross-functional integrator across brand teams, finance, compliance, and Patient Experience (PX).

Requirements

  • Bachelor’s degree
  • 5–7 years of relevant experience in vendor management, operations, or project management.
  • Strong project management skills with direct experience owning operational processes and driving tactical execution.
  • Excellence in communication and presentation skills, with proven ability to effectively engage and educate high-level, diverse audiences on brand and program strategies, translating complex recommendations into clear, actionable guidance.
  • Proven experience navigating and adhering to strict regulatory processes and compliance-driven environments.
  • Ability to manage, motivate, and hold external vendors accountable through clear communication and escalation management.

Nice To Haves

  • Prior experience within commercial affordability, patient access, in the pharmaceutical or biotechnology sector.
  • Proven track record of cross-functional leadership and influencing without authority within a complex matrixed organization.

Responsibilities

  • Own day-to-day operations for multiple commercial affordability programs across diverse brand and therapeutic areas.
  • Manage external vendor performance, driving accountability for SLAs, KPIs, service quality, and complex issue escalations.
  • Lead complex, cross-functional operational initiatives, including program launches, system enhancements, and regulatory updates.
  • Perform root-cause analysis on systemic operational issues and translate insights into scalable portfolio improvements.
  • Interpret program performance data (utilization, access, speed to therapy) to deliver actionable insights and maintain audit readiness.
  • Act as a primary subject matter expert and cross-functional integrator across brand teams, finance, compliance, and Patient Experience (PX).
  • Ensure strict program compliance with regulatory guidelines, internal policies, and operational guardrails.

Benefits

  • Discretionary annual bonus may be available based on individual and Company performance.
  • Benefits detailed at the link provided below.
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