Clinical Trial Manager

Immatics • Houston, TX

2d • Remote

About The Position

Join Immatics and shape the future of cancer immunotherapy; one patient at a time! Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.

Why Join Us?
Innovative Environment: Help to pioneer advancements in cancer immunotherapy.
Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
Global Impact: Contribute to therapies that make a lasting impact on patients globally.

Role Overview: We are seeking a Clinical Trial Manager (CTM) to support our U.S. Clinical Operations team. The CTM will oversee site management, monitoring oversight, and clinical trial operations activities to ensure compliance with GCP, regulatory requirements, and company SOPs. In this role, you will work closely with cross-functional teams and clinical sites to drive study execution, site engagement, and operational excellence across clinical trials.

Requirements

• Bachelor’s degree in life sciences, nursing, or a related field
• 2+ years of experience in on-site clinical monitoring
• 2+ years of Clinical Trial Manager experience within the pharmaceutical or biotechnology industry
• Strong knowledge of ICH-GCP, FDA, EMA, and applicable clinical trial regulations
• Demonstrated experience managing clinical trial sites, monitoring activities, and regulatory documentation
• Proficiency with clinical trial systems and tools (e.g., CTMS, eTMF, Microsoft Office)

Nice To Haves

• Experience in oncology clinical trials or related therapeutic areas
• Advanced ability to manage complex clinical operations processes and drive operational improvements
• Experience leading training initiatives for CRAs and clinical trial sites
• Demonstrated ability to drive quality, efficiency, and milestone achievement in fast-paced clinical environments
• Experience contributing to process harmonization, innovation, and continuous improvement initiatives
• Strong presentation, organizational, and cross-functional stakeholder management skills

Responsibilities

• Partner with Clinical Operations leadership to support clinical trial execution and monitoring activities in alignment with project goals
• Lead site feasibility, selection, initiation, and greenlight activities for clinical trial sites
• Develop and maintain study-specific operational plans, training materials, and monitoring documentation
• Oversee site management activities, including site engagement, regulatory submissions, and monitoring oversight
• Review trial progress, patient recruitment, and data quality metrics, and implement actions to support study objectives
• Provide guidance and oversight to CRAs, including trip report review and training support
• Manage protocol and GCP deviations and contribute to continuous improvement of clinical operations processes and procedures

Benefits

• Competitive rates for Health, Dental, and Vision Insurance
• 4 weeks of vacation, granted up front each year and prorated for first and last year of employment.
• 12 company paid holidays
• 7 days of sick time
• 100% employer-paid life insurance up to 1x annual salary, up to one hundred thousand dollars
• 100% employer-paid short- and long-Term disability coverage
• 401(k) with immediate eligibility and company match
• Partially paid parental leave for eligible employees.
• Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level