Clinical Trial Manager

IRE

1d • Remote

About The Position

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers. The Clinical Trial Manager (CTM) is responsible for the end-to-end operational oversight of assigned clinical trials, ensuring delivery against agreed timelines, budget, and quality standards. This includes oversight of site management (remote and onsite), clinical team activities, and compliance with regulatory requirements. The CTM leads Clinical Operations execution and serves as the primary point of accountability for trial delivery, working cross-functionally with internal teams and externally with sponsors.

Requirements

• Bachelor’s degree in life sciences or related field (or equivalent experience) with at least 1+ year of experience in a CTM or equivalent role (CRO or pharmaceutical environment)
• Experience managing Phase III and/or IV clinical trials across multiple therapeutic areas.
• Experience managing North American studies
• Ability to manage multiple studies and priorities in a fast-paced environment
• Strong leadership, organizational, and problem-solving skills
• Effective communication and stakeholder management skills
• Willingness to travel (~15%)

Nice To Haves

• Knowledge of risk-based monitoring (RBM) principles preferred

Responsibilities

• Plan and manage all clinical operations activities across assigned trials.
• Ensure delivery in line with scope, timelines, budget, and quality expectations.
• Oversee site lifecycle activities, including start-up, activation, monitoring, and close-out.
• Lead and oversee project specific operational activities of Clinical Research Associates (CRAs) and Site Management Associates (SMAs).
• Provide direction, training, and study performance oversight for clinical team members.
• Review monitoring reports, documentation, and study deliverables for quality and compliance.
• Develop and implement site management and monitoring plans.
• Oversee remote and onsite monitoring activities, including visit planning and execution.
• Ensure timely collection, review, and maintenance of trial documentation in CTMS.
• Proactively identify risks and implement mitigation strategies.
• Utilize metrics and dashboards to monitor study performance and quality.
• Support data review and query management activities as needed.
• Collaborate with cross-functional teams (Project Management, Data Management, Finance).
• Build and maintain strong relationships with sponsors and external partners.
• Provide status updates, metrics, and key study insights to stakeholders.
• Ensure adherence to ICH-GCP, regulatory requirements, and internal SOPs.
• Support audit and inspection readiness.
• Participate in bid defense activities as required.
• Contribute to process improvements and operational best practices.

Benefits

• Competitive base salary and performance related incentives
• Health and wellbeing programmes including medical, dental, and vision coverage where applicable
• Retirement and pension plans
• Life assurance and disability coverage
• Employee assistance programmes and wellbeing resources
• Learning and development opportunities through structured training and career pathways

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level