Clinical Research Project Manager

Mass General Brigham • Boston, MA

6d • $63,253 - $141,939 • Hybrid

About The Position

The Clinical Research Project Manager oversees ongoing and new research projects across the MGH Resilience and Prevention Program (RAPP) and the Emotion and Social Neuroscience Laboratory (ESNL), based at the Martinos Center for Biomedical Imaging and the MGH Psychiatry Department. The role manages multiple clinical studies, including randomized controlled trials, and directly hires, supervises, and trains Clinical Research Coordinators and other study staff. It coordinates study initiation, recruitment, intervention procedures, neuroimaging protocols, longitudinal data collection, and multi-site collaborations, while serving as a liaison among sponsors, the IRB, core laboratories, site principal investigators, study staff, and organizational partners.

The position manages program and project plans, schedules, budgets, workflows, timelines, risks, and reporting. It leads regulatory submissions and ongoing IRB compliance, maintains regulatory documentation under single-IRB oversight at MGB, and supports compliance with federal, state, and sponsor guidelines. Duties may also include building and managing REDCap instruments and case report forms, coordinating clinical-site data requests, and reviewing data quality. The position reports directly to the Principal Investigator and works closely with senior program managers, post-doctoral fellows, and clinical research coordinators.

RAPP develops and tests psychosocial interventions intended to increase emotional resilience among youth at risk for serious mental illnesses. ESNL studies neural correlates of emotion and social cognition abnormalities in people affected by or at risk for serious mental illnesses. The position may suit candidates interested in community-based mental health interventions, clinical neuroscience, prevention in at-risk youth, and outcomes research.

Requirements

• Bachelor's degree in a related field is required.
• Research-related experience; 5–7 years is preferred.
• Supervisory experience; 1–2 years is preferred.
• Ability to make independent, effective decisions.
• Strong organizational and communication skills.
• Ability to effectively supervise and train staff.
• Strong database management and computer skills, including REDCap, Microsoft Suite, R, and Python.
• Demonstrated analytical and problem-solving skills.

Nice To Haves

• MS, MA, MPH, MPP, another master's-equivalent degree, or higher.
• At least 2 years of experience at managerial levels in clinical research or grant coordination.
• Experience working in MRI environments; applicable but not required.
• Interest in community-based mental health interventions, clinical neuroscience, prevention of mental health conditions in at-risk youth, and outcomes research.

Responsibilities

• Manage multiple clinical research studies and oversee ongoing and new projects across RAPP and ESNL.
• Directly hire, supervise, train, guide, and support Clinical Research Coordinators and other study staff.
• Coordinate trial initiation, patient recruitment, study start-up, clinical intervention procedures, and neuroimaging research protocols.
• Oversee subject recruitment, intervention procedures, intervention fidelity, and longitudinal data collection events.
• Create, manage, and quality-assure standard operating procedures, study workflows, operations manuals, and project timelines.
• Serve as a liaison with sponsors, IRB, core laboratories, site principal investigators, study staff, and other stakeholders.
• Lead program and project planning, including schedules, budgets, plans, and alignment with organizational goals and strategic planning.
• Prepare project reports and presentations, provide regular updates to program leadership, and report study progress at investigators' meetings.
• Identify risks, issues, and challenges; recommend solutions and mitigation strategies; escalate issues; and address deviations from plans, timelines, or budgets.
• Coordinate cross-project initiatives and delegate work across project teams.
• Conduct research and manage data in research systems.
• Build and manage REDCap instruments and case report forms, including validation and branching logic, as needed.
• Coordinate data requests from clinical sites and conduct subsequent data-quality reviews.
• Lead IRB protocol submissions, modifications, continuing reviews, reportable new information, and consent revisions.
• Maintain the study regulatory binder under MGB single-IRB oversight and ensure compliance with federal, state, and sponsor guidelines, audits, and progress-reporting requirements.
• Communicate and coordinate cross-functionally with Research Management/Clinical Trials Office, MGB Healthcare Finance, scientific collaborators, NIH, FDA, and private foundations.
• Participate in developing and maintaining study policies and procedures.
• Develop advertising strategies to support recruitment activities.

Benefits

• Comprehensive benefits.
• Career advancement opportunities.
• Differentials, premiums, and bonuses as applicable.
• Recognition programs.
• Reasonable accommodation during the application or interview process and for performing essential job functions.

What This Job Offers

• Job Type: Full-time
• Career Level: Manager