Clinical Research Manager

TFS HealthScience

12d•Remote

About The Position

Join Our Team as a Clinical Research Manager (CRM) - home based in Argentina or Brazil. About this role As part of our Ohtalmology team you will working alongside passionate and innovative professionals to ensure our customers achieve their goals. The Clinical Research Manager (CRM) is responsible for coordinating and overseeing country and site management activities throughout study conduct, ensuring high‑quality delivery in accordance with company SOPs, regulatory requirements, and contractual obligations.

Requirements

Minimum 5 years of clinical monitoring experience in a CRO, pharmaceutical, or biotechnology environment.
At least 1 year of experience as a Clinical Research Manager (CRM) with proven oversight of site and country operations.
1+ years of experience in Ophthalmology (OPH), ideally within retina indications such as DME, AMD, GA, RVO, or inherited retinal diseases (IRDs).
Fluency in English, Spanish and Portuguese is required.
Strong understanding of ICH/GCP, regulatory requirements, and clinical operations processes.
Demonstrated ability to lead CRAs, manage study deliverables, and collaborate effectively with cross‑functional teams.

Responsibilities

Oversee day‑to‑day clinical operations to ensure delivery according to protocol, SOPs, ICH/GCP, and regulatory requirements.
Serve as the primary operational contact for Sponsors, providing updates, managing expectations, and ensuring high‑quality study execution.
Lead and support CRAs, including training, supervision, performance oversight, co‑monitoring, and review/approval of monitoring visit reports.
Ensure site and country performance through proactive review of monitoring activities, protocol deviations, data listings, recruitment progress, and issue escalation.
Maintain oversight of study documentation, including TMF quality, CTMS accuracy, monitoring plans, training plans, and study‑specific materials.
Collaborate with the Project Manager on study planning, investigator payments, resource allocation, study communications, and revenue forecasting.
Contribute to study meetings, Investigator Meetings, feasibility assessments, and, when required, local project management, CRA support, and bid defense activities.