Clinical Research Manager Licensed (RN) - Medicine Clinical Trials Office

Mount Sinai Health System • New York, NY

5d • Onsite

About The Position

The Clinical Research Manager Licensed has oversight of the research projects within a department or division. Assists the Principal Investigator (P.I.) in preparing and negotiating clinical trials care delivery, patient eligibility, budgets, adequate staffing and all related HR activity.

The Clinical Trials Office is seeking a highly skilled Clinical Research Nurse manager to lead and support and support a growing portfolio of cellular therapy clinical research, with primary focus on non-malignant CAR-T and cellular therapy studies, while providing transitional collaboration of malignant Bone Marrow Transplant (BMT)/Cellular Therapy programs.

This role will initially focus on the coordination and implementation of complex clinical research studies involving CAR-T cell therapy and non-malignant cellular therapy (50% effort) and support of malignant Bone Marrow Transplant (BMT/Cellular Therapy) activities for 50% effort. Over time, the non-malignant effort will grow, and the malignant effort will decrease. The role will ensure participant safety, protocol adherence, and regulatory compliance while collaborating with principal investigators and multidisciplinary teams to achieve successful study execution and maintain data integrity.

This role involves direct patient interaction, ensuring the safety and well-being of study participants, adhering to study protocols, and maintaining regulatory compliance. This position is ideal for a highly organized professional who thrives in a fast-paced environment and excels at managing complex workflows, regulatory documentation, and multi-study coordination. Under minimal supervision, the Clinical Research function includes studies of increased complexity. The position features a dual reporting structure to Tisch Cancer Institute and to Departmental Clinical Research teams with and without nursing licensure, requiring strong communication and adaptability. Responsibilities and assigned program areas may evolve over time based on departmental programmatic needs.

This role is critical to supporting the strategic expansion of non-malignant cellular therapy research while maintaining excellence in clinical care, regulatory compliance, and operational efficiency. The Nurse Manager will play a central role in scaling innovative therapies, leading teams, and ensuring successful study execution across a growing and complex portfolio.

Requirements

• Licensed Clinical Research Manager (RN)
• Highly skilled Clinical Research Nurse manager
• Highly organized professional
• Ability to thrive in a fast-paced environment
• Ability to excel at managing complex workflows, regulatory documentation, and multi-study coordination.
• Strong communication skills
• Adaptability

Nice To Haves

• Experience with non-malignant CAR-T and cellular therapy studies.
• Experience with malignant Bone Marrow Transplant (BMT)/Cellular Therapy programs.

Responsibilities

• Oversight of research projects within a department or division.
• Assists the Principal Investigator (P.I.) in preparing and negotiating clinical trials care delivery, patient eligibility, budgets, adequate staffing and all related HR activity.
• Coordination and implementation of complex clinical research studies involving CAR-T cell therapy and non-malignant cellular therapy.
• Support of malignant Bone Marrow Transplant (BMT/Cellular Therapy) activities.
• Ensure participant safety, protocol adherence, and regulatory compliance.
• Collaborate with principal investigators and multidisciplinary teams to achieve successful study execution.
• Maintain data integrity.
• Direct patient interaction, ensuring the safety and well-being of study participants.
• Adhering to study protocols.
• Maintaining regulatory compliance.
• Managing complex workflows, regulatory documentation, and multi-study coordination.
• Scaling innovative therapies.
• Leading teams.
• Ensuring successful study execution across a growing and complex portfolio.

Benefits

• Strength through Unity and Inclusion
• Commitment to fostering an environment where everyone can contribute to excellence.
• Common dedication to delivering outstanding patient care.
• Opportunity to join Mount Sinai’s unparalleled legacy of achievement, education, and innovation.
• Encouragement to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.
• Leaders committed to fostering a workplace where all employees feel valued, respected, and empowered to grow.
• Environment where collaboration, fairness, and continuous learning drive positive change.
• Supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally.

What This Job Offers

• Job Type: Full-time
• Career Level: Manager