Clinical Development Scientist, Director--Inflammation and Immunology (I&I) Non MD

Pfizer • Cambridge, MA

5d • $176,600 - $294,300 • Hybrid

About The Position

The Clinical Development Scientist will lead and coordinate the development of multiple clinical studies for novel biologic and small molecule therapies at various stages of clinical development within the Inflammation and Immunology (I&I) therapeutic area. The role leads clinical protocol development and contributes as an individual member of clinical study teams to support enrollment and delivery timelines. It works closely with cross-functional partners—including Research Unit Clinicians, Global Clinical Leads/Medical Monitors, Biostatistics, Clinical Pharmacology, Precision Medicine, and Digital Medicine—to ensure I&I perspectives are represented in study teams.

The position contributes to drug development across the development continuum and serves as a key member of clinical sub-teams, ensuring collaboration and connectivity across functions. It provides scientific leadership for study design, execution, and interpretation; supports development strategy and milestones; leads clinical data review; and partners with internal and external experts to incorporate current scientific and clinical insights into development plans. The role also helps ensure compliance with GCP, regulatory requirements, IRB requirements, and Pfizer standards, and supports continuous process improvement.

This is a hybrid role requiring an average of 2.5 days per week onsite, with the employee required to be commutable to the site. Occasional travel of 5–10% is expected. Relocation support may be available. The annual base salary range is $176,600 to $294,300, with eligibility for a 20% target bonus under Pfizer’s Global Performance Plan and participation in a share-based long-term incentive program.

Requirements

• PhD or PharmD and at least 5 years of relevant industry experience in clinical development, clinical research, or a related drug development role, with a demonstrated track record of supporting development programs through key milestones; or
• MS and at least 7 years of relevant industry experience in clinical development, clinical research, or a related drug development role, with a demonstrated track record of supporting development programs through key milestones; or
• BSc and at least 8 years of relevant industry experience in clinical development, clinical research, or a related drug development role, with a demonstrated track record of supporting development programs through key milestones.
• Deep understanding of the biopharmaceutical environment and clinical drug development, with familiarity across related disciplines including Biostatistics, Regulatory Affairs, Clinical Pharmacology, and Pharmaceutical Sciences.
• Experience developing and coaching others, guiding cross-functional teams, and driving meaningful business impact.
• Strong scientific writing, presentation, and verbal communication skills.
• Experience building consensus, influencing stakeholders, and driving change across all organizational levels, including senior leadership.
• Strong experience reviewing clinical data listings and interpreting study data.
• Ability to perform complex data analysis.
• Must be authorized to work in the United States; U.S. work visa sponsorship is not available.
• Must have permanent work authorization in the United States.

Nice To Haves

• Experience in Immunology clinical development.
• Experience supporting Phase 2, Phase 3, and/or late-stage clinical development programs.
• Breadth of diverse leadership experiences and capabilities, including influencing and collaborating with peers, developing and coaching others, and overseeing and guiding colleagues’ work to achieve meaningful outcomes and business impact.

Responsibilities

• Provide scientific leadership for the design, execution, and interpretation of clinical studies, including innovative study designs, high-quality trial execution, safety assessments, and clinically meaningful outcomes.
• Lead and support clinical development programs, operating independently within project teams.
• Serve as a technical resource for clinical issues raised by internal and external collaborators, investigators, consultants, and contractors.
• Support development of publications, abstracts, presentations, and scientific communications.
• Participate in project teams to support clinical development strategy, study implementation, and key milestones, including study startup, conduct, and delivery.
• Lead preparation of clinical protocols and lead or contribute to informed consent forms, study training materials, investigator brochures, statistical analysis plans, and regulatory documents.
• Lead clinical data review, including collection, analysis, and interpretation of safety and efficacy data for safety review meetings and ongoing review activities in accordance with data review plans.
• Collaborate with study teams to maintain open communication and support successful study execution and completion.
• Foster transparent, trusting partnerships across teams, sub-teams, and therapeutic areas.
• Develop effective partnerships with project leaders and cross-functional colleagues, including Biostatistics, Regulatory Affairs, Clinical Pharmacology, and Clinical Operations.
• Manage priorities and accountability across multiple project teams, core study teams, and clinical sub-teams to support study startup, conduct, and closeout.
• Develop expertise in Pfizer clinical processes, checklists, and SOPs, and ensure compliance with GCP, regulatory requirements, IRBs, and Pfizer standards; apply learnings to support process improvement.
• Develop expertise in Pfizer compliance systems, registries, and study systems, including GDMS, pTMF, Clinical Trial Registries, CORD, JReview, and Signal Management, and apply lessons to improve study execution.
• Partner with relevant functions to incorporate biomarker strategies into therapeutic-area programs for patient stratification, efficacy assessments, and clinical development objectives.
• Establish and maintain relationships with external experts, consultants, KOLs, regulators, and disease-specific investigator networks to incorporate evolving insights into development plans and study designs and support study conduct, data interpretation, and dissemination of results.
• Maintain current knowledge of scientific and clinical literature relevant to I&I therapeutic areas and clinical development strategies.

Benefits

• 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution.
• Paid vacation, holidays, and personal days.
• Paid caregiver/parental and medical leave.
• Medical, prescription drug, dental, and vision coverage.
• Eligibility for participation in Pfizer’s Global Performance Plan with a 20% target bonus.
• Eligibility to participate in a share-based long-term incentive program.
• Relocation assistance may be available based on business needs and/or eligibility.

What This Job Offers

• Job Type: Full-time
• Career Level: Director