Clinical Development Medical Director- Pain

Vertex Pharmaceuticals•Boston, MA

4d•$240,000 - $360,000•Hybrid

About The Position

The Clinical Development Medical Director serves as the Medical Lead for Vertex clinical trials, collaborating with cross-functional, multidisciplinary study teams on clinical trial strategy, design, and execution. The position also serves as Medical Monitor, responsible for monitoring the safety of enrolled subjects on assigned trials. The incumbent works across multiple trials in all phases of clinical development and may participate in other selected clinical development projects. The role leads development of key study documents, supports study execution and regulatory submissions, provides scientific and clinical input to study-related documents and analysis plans, and liaises between Translational Medicine/Clinical Development and other internal groups. It also represents Vertex to external medical personnel in developing protocols and conducting studies. The role requires an MD, DO, or equivalent ex-US medical degree; board certification or eligibility in a specialty field is highly desired. It typically requires 10 years of basic or clinical research experience, or an equivalent combination of education and experience, as well as experience designing, executing, and analyzing clinical trials. Vertex encourages continuous learning and thoughtful adoption of advances in AI, technology, automation, and industry trends to improve decision-making, innovation, efficiency, and patient outcomes. The position is hybrid-eligible or on-site-eligible. Employees may choose to work remotely up to two days per week in the hybrid designation, or on-site five days per week with ad hoc flexibility. Flex status is subject to Vertex policy and may change. The stated base salary range is $240,000–$360,000. The role is eligible for an annual bonus and annual equity awards; some roles may also be eligible for overtime pay. Vertex describes its benefits as including medical, dental, and vision coverage, generous paid time off, a week-long summer and winter company shutdown, educational assistance programs including student loan repayment, a commuting subsidy, matching charitable donations, and a 401(k).

Requirements

MD, DO, or equivalent ex-US medical degree.
Board certification or eligibility in a medical, pediatric, or surgical subspecialty; board certification or eligibility in a specialty field is highly desired.
Typically requires 10 years of basic or clinical research experience in an academic or industry setting, or an equivalent combination of education and experience.
Experience analyzing research data and publications.
Working knowledge of biostatistics, Good Clinical Practice (GCP), scientific and clinical research methods, and clinical study design.
Experience with the design, execution, and analysis of clinical trials.
Excellent oral and written communication skills.
Ability to collaborate in a fast-paced, team-based, matrix environment and function independently as appropriate.
Effectiveness in building cross-functional alliances based on end-to-end drug development thinking and experience.

Nice To Haves

Board certification or eligibility in a specialty field is highly desired.

Responsibilities

Lead development of study protocols, investigator brochures, clinical development plans, and other key study documents with other line functions and minimal guidance.
Serve as Medical Monitor for assigned clinical studies.
Serve on cross-functional Study Execution Teams for assigned trials and work with team members to achieve efficient, high-quality study execution.
Participate in preparing regulatory submission documents, including clinical sections of INDs and CTAs, safety reports, annual reports, responses to regulatory authorities and Ethics Committees/IRBs, and other appropriate documents.
Provide scientific and clinical input to study-related documents and analysis plans, including informed consent forms, clinical research forms, statistical analysis plans, clinical pharmacology analysis plans, and clinical study reports.
Act as liaison between Translational Medicine/Clinical Development and other internal Vertex groups, such as Regulatory Affairs and Clinical Operations, for assigned studies.
Represent Vertex to outside medical personnel in development of clinical protocols and study conduct.
Perform other duties related to clinical programs as assigned.
Monitor the safety of enrolled subjects on assigned trials.

Benefits

Annual bonus eligibility
Annual equity awards
Medical benefits
Dental benefits
Vision benefits
Generous paid time off, including a week-long company shutdown in the summer and winter
Educational assistance programs, including student loan repayment
Commuting subsidy
Matching charitable donations
401(k)
Some roles may be eligible for overtime pay