Clinical Development Medical, Associate Director

Pfizer • Pearl River, NY

2d • Hybrid

About The Position

The Clinical Development Medical Associate Director serves as a clinician within a Pfizer vaccine development program. The role may lead one or more studies and works closely with the global clinical program lead, who is accountable for execution of the overall program. As part of a matrix team, the clinician helps execute studies, perform medical monitoring, support regulatory interactions, and lead study-team clinical deliverables. The position provides medical and scientific expertise and oversight for clinical trials and serves as the point of accountability for the design, execution, monitoring, delivery, and reporting of assigned studies, with a focus on patient safety.

The clinician is accountable for study safety, including medical advice for risk assessment and mitigation, adherence to the Safety Surveillance Review Plan, review of individual and cumulative safety data, medical context for adverse-event reports, and communication of safety information to study sites. The role contributes medical input to protocol development, clinical development plans, country feasibility, and study-team documents and plans.

The role supports study conduct through clinical input on study materials and processes, vendor selection, data quality, analysis and reporting, protocol-specific training, site interactions, committee interactions, investigator compliance, issue resolution, closeout, audit responses, and inspection readiness. Under supervision, the clinician also authors clinical sections of regulatory documents, may co-author scientific publications and presentations, may contribute to protocol budget execution, and may support interactions with regulatory authorities, key opinion leaders, and principal investigators.

This is a hybrid role requiring residence within commuting distance and an average of 2.5 on-site workdays per week. The annual base salary range is $189,200 to $315,400, with eligibility for a 22.5% bonus target and a share-based long-term incentive program. Relocation assistance may be available based on business needs and eligibility. Candidates must be authorized to work in the U.S.; work visa sponsorship is not available.

Requirements

• Medical degree (M.D., D.O., or equivalent).
• Licensed by a health authority to prescribe medicines independently for at least one year after the intern/houseman year.
• At least two aggregate years of using the prescribing license in a patient-care setting.
• 0–4 years of work experience.
• Ability to critically evaluate medical and scientific information.
• Excellent written and oral communication skills.
• Understanding of the design, development, and execution of clinical programs and studies.
• Ability to adapt to a fast-paced and changing environment.
• Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and productivity.
• Curiosity about how AI tools can improve outcomes and understanding of responsible AI practices, including risk management and ethical use.
• Must be authorized to work in the United States; U.S. work visa sponsorship is not available.
• Must have permanent work authorization in the United States.

Nice To Haves

• Documented work experience or knowledge of statistics.
• Training and experience in infectious diseases and/or hospital infection control.
• Experience with investigational clinical trials.
• Demonstrated breadth of leadership experience, including influencing and collaborating with peers, developing and coaching others, and guiding colleagues’ work to achieve meaningful outcomes and business impact.

Responsibilities

• Provide medical advice for study risk assessment and mitigation to support quality, compliance, and patient safety.
• Ensure development of and adherence to the Safety Surveillance Review Plan and perform or oversee regular review of individual and cumulative safety data.
• Monitor study safety issues and provide medical context for serious adverse event and adverse event reports.
• Participate in Safety Review Team activities and review literature as needed to address safety questions.
• Communicate safety information to study sites and respond to site questions about safety.
• Contribute medical input to protocol development, updates to the clinical development plan, and country feasibility.
• Work with medical monitors to ensure study documents meet regulatory requirements and company policy and are reviewed by IRBs or IECs.
• Provide clinical input to study-team materials and plans, including monitoring guidelines, statistical analysis plans, informed consent documents, clinical review forms, data edit checks, and data quality plans.
• Contribute to CRO and vendor selection and ensure medical and technical requirements for data integrity are applied.
• Work with the study team to support high-quality data, appropriate patient populations, and adequate clinical assessments.
• Contribute to medical review and interpretation of efficacy and safety data, including delivery of top-line results and clinical study reports with relevant collaborators.
• Provide protocol-specific training to study teams, investigators, clinical research associates, and others.
• Interact with healthcare professionals at study sites and with Data Monitoring Committees and steering committees as required.
• Notify appropriate study personnel when investigators need to be informed of changes in research activity or significant new adverse events.
• Monitor investigator compliance with protocol and regulatory requirements.
• Support issue resolution, study closeout, audit responses, and inspection readiness.
• Under supervision, author clinical sections of regulatory documents, including Investigator Brochures, annual reports, Investigational New Drug sections, and clinical study reports.
• Contribute to abstracts, posters, presentations, and publications as appropriate.
• May contribute to protocol budget execution.
• Support interactions with regulatory authorities and provide responses as needed.
• Liaise with key opinion leaders and principal investigators in countries to build networks for new trials.

Benefits

• Participation in Pfizer’s Global Performance Plan, with a bonus target of 22.5% of base salary.
• Eligibility to participate in a share-based long-term incentive program.
• 401(k) plan with Pfizer matching contributions and an additional Pfizer Retirement Savings Contribution.
• Paid vacation, holidays, and personal days.
• Paid caregiver/parental and medical leave.
• Medical, prescription drug, dental, and vision coverage.
• Relocation assistance may be available based on business needs and/or eligibility.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree